- Lilly (Indianapolis, IN)
- …Director of Upstream Process Development will oversee the development of drug substance upstream processes for biologics within Lilly's biologics and ... Lead and manage a proficient team of scientists and engineers accountable for upstream process development endeavors. These encompass various activities such as … more
- Amgen (Holly Springs, NC)
- …Let's change the world. In this vital role you will be a part of the Process Development Drug Substance Technology group at Amgen's FleX Batch Biologics ... role. Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the...plan to be a carbon-neutral company by 2027. **Engineer Upstream , Process Development** **Live** **What you will… more
- Astellas Pharma (South San Francisco, CA)
- …development to adapt new types of rAAV and improve drug substance quality, yield, manufacturability and efficiency. Deliver process improvements which reduce ... the knowledge of physicochemical properties of biopharmaceuticals + Perform experiments of upstream process , cell culture, passage and transfection for rAAV… more
- Amgen (Holly Springs, NC)
- …in this meaningful role. Be part of Amgen's newest and most sophisticated drug substance manufacturing plant. When completed, the Amgen FleX batch facility ... Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry...be a carbon-neutral company by 2027. Automation Engineer - Upstream Delta V **Live!** **What you will do** Let's… more
- Endo International (Horsham, PA)
- …fermentation and production support areas to manufacture collagenase clostridium histolyticum bulk drug substance (CCH BDS). This role authors and revises ... our team. **Job Description Summary** The Manufacturing Associate II, Upstream Processing works in a hands-on capacity in the...manufacturing and process equipment documentation and is responsible for supporting necessary… more
- System One (Exton, PA)
- …whose purpose is to produce material for preclinical, clinical, and commercial biologics drug substance to support pipelines. Execution of manufacturing in the ... M-F Full Time Type: Contract Responsibilities: Under supervision and guidance, the Process Technician of Upstream Operations will be responsible for hand-on… more
- Merck (Rahway, NJ)
- …and characterize robust clinical processes capable of delivering multi-kilogram quantities of drug substance + Independently design and conduct experiments for ... community to influence the field. BPR&D includes three lab-facing technical functional areas: Process Cell Sciences (PCS), Upstream and Downstream Process … more
- Daiichi Sankyo Inc. (Basking Ridge, NJ)
- …experience in CMC related functions including (mAb, Drug Substance , Drug Product, or New Modality) process and product development preferred **Travel** ... areas centered around rare diseases and immune disorders. **Summary** The Technology Management (mAb, Drug Substance , Drug Product, or New Modality) Lead is… more
- Sanofi Group (Framingham, MA)
- …upstream IND and BLA sections and support agency responses + Lead cross-functional drug substance development teams + Lead innovation projects to develop and ... for the company. + Lead a group of scientists focused on upstream process development and oversee their professional development + Serve as a subject… more
- Amgen (Thousand Oaks, CA)
- …in developing process control strategies in Clinical/Commercial Drug Substance Plant Operations. + Familiarity with Upstream and Downstream unit ... & Engineering (MCS-F&E) Automation team you will support Clinical and Commercial Drug Substance plant operations This includes complex and challenging system… more
- Sanofi Group (Waltham, MA)
- …viral vectors (AAV), non-viral and cell therapy products. This 6-month position centers on drug substance process development for gene therapy but will ... engineering, or biological engineering with relevant study experience. + Understanding of drug substance purification process concepts. + Theoretical and… more
- Catalent Pharma Solutions (Bloomington, IN)
- …is a state-of-the-art, GMP manufacturing facility, providing one million sq/ft of drug substance manufacturing, drug product manufacturing, and related ... pharmaceutical services. This award-winning facility helps customers accelerate biologic drug development programs and bring better treatments to help patients live… more
- Catalent Pharma Solutions (Madison, WI)
- … cell culture, downstream protein purification, mRNA production and filling of Drug Substance . Candidates should possess strong technical writing skills and ... market leading biologics analytical services as well as SMARTag Antibody Drug Conjugate technology in Emeryville, CA. Leveraging our growing differentiated… more
- Sanofi Group (Framingham, MA)
- …is part of the Global MSAT Pilot Lab Cell Culture team in the drug substance function within global Manufacturing Science, Analytics and Technology (MSAT) and ... **Sr. Associate Scientist, Upstream , Pilot Lab** **DEPARTMENT DESCRIPTION** : The Senior...licensure, ongoing commercial manufacturing, and life-cycle management activities. The drug substance (DS) function within global MSAT… more
- Amgen (Holly Springs, NC)
- …help design and perform experiments at the bench scale that span the end-to-end Drug Substance process , covering cell culture and/or purification operations. ... vital role you will be a part of the Process Development Drug Substance Technology...the integrated group. + Apply a fundamental understanding of Upstream (Cell Culture) bioprocessing to support biologics technology transfer,… more
- Belcan (Thousand Oaks, CA)
- …from other countries) Seeking a Process Development Engineer to join the Drug Substance Technology Engineering team at our Thousand Oaks facility. Providing ... staff, the Engineer performs the following: - Transfer cell culture processes for drug substance manufacturing and performs process improvements from the… more
- Catalent Pharma Solutions (Madison, WI)
- …(IVT) reactions, chromatography, tangential flow filtration (TFF), viral filtration, bulk drug substance filling, and column packing/qualification + Performs ... advanced troubleshooting during chromatography, TFF, viral filtration, IVT reactions, bulk drug substance filling, and column packing/qualification + Accurately… more
- ThermoFisher Scientific (St. Louis, MO)
- …+ Leads the Manufacturing Science and Technology team and is responsible for process related activities enabling Drug Substance manufacturing of Biologic's. ... process improvements and scientific expertise in the Drug Substance field + Provides strong technical...a fast-paced production environment. + Broad experience in all process areas ( Upstream cell culture, downstream processing,… more
- University of Washington (Seattle, WA)
- …Specialist (NE S 8). **POSITION PURPOSE** The Center for Medication Development for Substance Use Disorders and Overdose, directed by Dr. Marco Pravetoni, at the ... therapeutics, and small molecule pharmacotherapies to counteract opioid use disorders, drug overdoses, and the translation of these promising novel therapies into… more
- Catalent Pharma Solutions (Harmans, MD)
- …Process Development, Manufacturing, and Quality to ensure successful implementation of cGMP drug substance and drug product manufacturing processes. **The ... the manufacturing group, including the transfer between external clients or Process Development and Manufacturing. The director is responsible for leading the… more