- Voyager Therapeutics (Lexington, MA)
- …Inc. Job Summary Voyager Therapeutics is seeking a motivated Senior Scientist* , Oligonucleotide Chemistry to join our growing Non-Viral Team. This role will work ... oligonucleotides (ASOs) and/or siRNAs candidates to enable Voyager's brain-penetrant antibody- oligonucleotide conjugate (AOC) pipeline. This position is an opportunity… more
- Eli Lilly and Company (Boston, MA)
- …the development of genetic medicines which includes active investments in Oligonucleotide development, nanomedicines for tissue specific targeting and other gene ... delivery strategies. The drug product team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, Antibody Drug Conjugates and AAV and other non-viral vector delivery. We are seeking highly motivated… more
- Katalyst HealthCares and Life Sciences (Cambridge, MA)
- …small molecule development compounds, including chemical drug, peptide and oligonucleotide . good understanding of CMC requirements for clinical trial applications ... and marketing applications for small molecules. Managing expectations on deliverables to meet tight timelines. Handling timeline pressure. Cultivating business relationships with GRA, CMC teams, RegOps, CDDC, GRA regions and local affiliates. bility to quickly… more
- Lilly (Boston, MA)
- …and LC-MS method development, along with a solid understanding of oligonucleotide synthesis and downstream processing. The successful candidate will be responsible ... Build and lead a high-performing analytical team to support an oligonucleotide -based drug discovery program, including recruiting, mentoring, and managing scientists… more
- University of Michigan (Ann Arbor, MI)
- Oligonucleotide Synthesis Chemist Postdoctoral Research Fellow Apply Now **Job Summary** The Nucleic Acid Therapeutics Core is a newly initiated program at the ... for early stage research and development. Our team seeks a highly motivated Oligonucleotide Synthesis Chemist Postdoctoral Research Fellow to be part of building our… more
- Lilly (Indianapolis, IN)
- …to join our engineering group within its early phase TIDES (peptide and oligonucleotide ) team. The engineer will join a highly dynamic and cross-functional team ... experiments related to solid phase and liquid phase peptide and oligonucleotide synthesis, and downstream purification and isolation. + Develop drug substance… more
- Lilly (Indianapolis, IN)
- …the world. Eli Lilly and Company seeks a Sr. Engineer - Oligonucleotide (R2-R4) to develop automation solutions and manufacturing processes for oligonucleotide ... drug substances. Write automation programs needed for new synthesizers and unit operations. Provide automation technical leadership and project management for engineering projects. Design and execute laboratory experimentation. Generate creative solutions for… more
- Lilly (Indianapolis, IN)
- …approaches to oligonucleotides and their conjugates as well as oligonucleotide purification, isolation, and formulation. The position presents an opportunity ... support clinical trials, product commercialization, and regulatory submissions of oligonucleotide therapeutics. Developing and working with both internal manufacturing… more
- US Tech Solutions (Lexington, MA)
- …development** **2. Mass Spec Maintenance and trouble shooting** **3. Oligonucleotide Purification** **Job Description:** Seeking a highly motivated Associate ... Scientist II to join the Oligonucleotide Chemistry Team in Lexington, Massachusetts. The candidate will be responsible for analysis and purification of… more
- J&J Family of Companies (San Diego, CA)
- …J&J IM is seeking a highly motivated postdoctoral scholar specialized in Oligonucleotide chemistry to join our fast-paced Cell and Genetic Medicine Team in ... J&J organization. You will be responsible for: + Drive innovation in oligonucleotide chemistry includes design, solid phase synthesis, and characterization of novel … more
- AbbVie (North Chicago, IL)
- …motivated candidate with experience in the characterization of peptide and oligonucleotide biomolecules. The successful candidate will be responsible for leading the ... advanced analytical characterization methods to support complex peptide and oligonucleotide development programs. + Utilize cutting-edge structure elucidation techniques… more
- Lilly (Indianapolis, IN)
- …activities to support clinical trials and regulatory submissions of peptide/ oligonucleotide therapeutics. Developing and working with both internal manufacturing ... this position will be expected to: + Synthesize complex peptide/ oligonucleotide active pharmaceutical ingredients (APIs) using both established and ground-breaking… more
- Alloy Therapeutics (Waltham, MA)
- …underlying intellectual property which implements a novel spatial conformation of the oligonucleotide developed by Sudhir Agrawal of Arnay Sciences. The team works ... of postdoctoral experience. Our research involves experiments with RNA biology, Oligonucleotide chemistry, Antisense and siRNA designs, Gene editing and mRNA… more
- Lilly (Lebanon, IN)
- …to provide support to the Lebanon small molecule, peptide, and oligonucleotide manufacturing processes. Responsibilities include outfitting the TS/MS lab that is ... portfolio + Understand the scientific principles of small molecule, peptide, and/or oligonucleotide manufacturing + Support site leadership to build a diverse and… more
- Danaher Corporation (Bothell, WA)
- …ensure performance within expected parameters. This position is part of the Oligonucleotide Manufacturing team and will be located onsite in Bothell, Washington ... if you also possess previous experience in: + Knowledge of solid phase oligonucleotide synthesis + Manual pipetting and/or liquid formulation + Prep or Semi-Prep… more
- LGC Group (Petaluma, CA)
- …and a leading provider of CRO / CDMO capability to the therapeutic oligonucleotide discovery and development industry. Centred out of LGC's site in Kulmbach, ... and clinical development. Our site in California has been involved in oligonucleotide synthesis for three decades and established the therapeutics activity in 2019.… more
- LGC Group (Petaluma, CA)
- …whose active ingredients are chemically derived from DNA or RNA. They are called oligonucleotide or nucleic acid therapeutics. We use our many years of expertise to ... support the Quality Assurance function at our brand new therapeutic GMP oligonucleotide facility. You will collaborate with various GMP functions to refine, develop,… more
- Lilly (Lebanon, IN)
- …pilot plant facility in Lebanon with a focus on peptide and oligonucleotide synthesis. This position involves solving technical challenges with equipment design, ... drug substance active pharmaceutical ingredient (API) manufacturing for peptide and oligonucleotide synthesis. + Perform impact and risk assessments for the peptide… more
- Lilly (Lebanon, IN)
- …process chemistry + Demonstrated basic knowledge in small molecule, peptide, or oligonucleotide API Manufacturing. + Relevant industrial experience in any of the ... following discipline such as API Manufacturing, TS/MS (Technical Services/ Manufacturing Sciences), Quality Control, Quality Assurance, or Development. + Familiarity with cGMP manufacturing environment and terminology. + Excellent analytical, interpersonal,… more
- Lilly (Indianapolis, IN)
- …Skills/Preferences:** + Hands-on experience in synthetic peptide and/or oligonucleotide manufacturing. + Proven leadership or supervisory experience, with ... a demonstrated ability to guide and support team members. + Proficiency in computer applications relevant to laboratory and manufacturing operations. + In-depth knowledge of Current Good Manufacturing Practices (cGMPs) and regulatory expectations. + Excellent… more
