- Merck & Co. (Boston, MA)
- …seeking a highly motivated Associated Principal Scientist with wide knowledge of pharmacokinetic ( PK ) and toxicokinetic (TK) principles and modeling techniques. ... pharmacokinetic modeling (NCA analysis, nonparametric superposition, and compartmental PK modeling), and drug metabolism is required with demonstrated hands-on… more
- Merck & Co. (San Francisco, CA)
- …for optimizing model-informed development- Responsible for developing and executing population pharmacokinetic models, PK / PD models, ER models, MBMA, ... of the following pharmacometrics capabilities such as population pharmacokinetics (popPK), PK / PD models, exposure response (ER) models, model-based meta-analysis… more
- Merck & Co. (South San Francisco, CA)
- …biopharmaceutical companies. Responsibilities: Develop model-based strategies ( translational PK / PD strategies, mechanistic model, POPPK/ PD , ... Point, PA / Rahway, NJ is seeking a curious and collaborative Associate Director to support our rapidly expanding cardiometabolic and ophthalmology pipelines. - As… more
- Merck & Co. (Boston, MA)
- …basis in decision making and driving pipeline impact: population pharmacokinetics ( PK ) and pharmacodynamics ( PD ) analysis, model-based meta-analysis (MBMA), ... our company, this position offers an opportunity for the Director to drive pipeline impact and mentor/coach a talented...engineering, or a related fieldExtensive experience in performing population PK and PK / PD analyses using… more
- Merck & Co. (Rahway, NJ)
- …programming deliverables for global stakeholders in Early Development Statistics and PK / PD Modeling and Simulation spanning all therapeutic areas except ... programming expertise with clinical endpoint data (efficacy and safety) and pharmacokinetic data (raw concentration data, derived PK parameters).Significant… more
- Merck & Co. (Rahway, NJ)
- …data sources.Programmatically develop, validate and maintain modeling-ready datasets by integrating PK , PD and covariate data.Produce tables and graphics for ... Support statistical programming analysis and reporting deliverables for global PK modeling and simulation stakeholders spanning all therapeutic areas.Develop and… more
- Daiichi Sankyo, Inc. (Bernards, NJ)
- …with Translational Medicine and Clinical Pharmacology to ensure appropriate biomarker, PK / PD measurements; Reviews emerging clinical data regularly; ... Initiates contact w/KOL and prepares material for KOL interactions on a program based need; Involvement with in-licensing and acquisitions on individual due… more
- Clinical Dynamix, Inc. (Florham Park, NJ)
- …responsible for designing clinical studies and performing, interpreting, and reporting Pharmacokinetic / Pharmacodynamic ( PK / PD ) results. This individual ... constructing, validating, and implementing disease, placebo, exposure response, and appropriate PK / PD models to evaluate risk/benefit and facilitate drug… more
- BioSpace (Tarrytown, NY)
- …life of a Director may look like: Manages and is accountable for the PK / PD evaluation of a small portfolio of products or projects. Works independently, with ... be the right role for you if you: Are fully knowledgeable of pharmacokinetic / pharmacodynamic principles, pharmacology, biology, and quantitative aspects of drug… more
- Revolution Medicines (Redwood City, CA)
- … PK (PBPK), quantitative systems pharmacology (QSP), and semi-mechanistic PK / PD models to support discovery and development-phase projects. Propose ... understanding of the core concepts, assumptions, and limitations associated with PK / PD modeling Experience with development, calibration, and validation of… more
- Bexorg, Inc. (New Haven, CT)
- …findings from preclinical studies into clinically actionable endpoints. Build quantitative PK / PD and exposure-response models linking biomarker changes to ... spatial/transcriptomic, single-cell omics, proteomics, and metabolomics techniques. Experience building PK / PD and exposure-response models. Proven ability to… more
- Providence Medical Center (Kansas City, KS)
- …and regulatory standards. This position is on a per diem basis, meaning PD /PRN. Shift's Available: Variable shifts - Day, Evening or Weekend Options Employment Type: ... Per Diem ( PD /PRN) Hours: 8-hour Variable Shift Location : Providence Medical...of the drug distribution systems including patient counseling and pharmacokinetic calculations Participates in performance improvement and data collections… more
- General Proximity (San Francisco, CA)
- …cell biology, pharmacology, DMPK, safety assessment, and CMC Preclinical PK / PD /efficacy relationships and their clinical translation Collaborating with ... regulatory, CMC, and clinical groups to develop strategic regulatory paths for approval Collaborating with external CROs, academic partners, and other organizations to accelerate discovery and development efforts Overseeing a portfolio of drug discovery… more
- Charles River (Mattawan, MI)
- …body fluids and tissue from non-regulated and regulated safety evaluation, pharmacokinetic / pharmacodynamic studies. Staff participate in the development and ... validation of quantitative LC/MS/MS methodology, sample analysis, and interpretation & reporting of data utilizing validated hardware and software systems. This includes the development of sample extraction techniques and employment of laboratory robotics to… more
- Eli Lilly and Company (Indianapolis, IN)
- …in both Discovery and Development (eg. Toxicology, Pharmacology, Chemistry, Clinical PK / PD , Clinical Pharmacology, Regulatory, and Medical) to assess drugability ... partner to apply innovative PBPK approaches to translate and predict human PK , inform clinical plans and support registration. *Communicate the value of mechanistic… more
- Kodiak Sciences Inc (Palo Alto, CA)
- …environment. Key Responsibilities Design and execute preclinical efficacy, pharmacokinetics/pharmacodynamics ( PK / PD ), and ex vivo studies to support early-stage ... Evaluate emerging technologies and develop novel assays to accelerate program timelines and expand mechanistic understanding. Maintain meticulous experimental… more
- Boehringer Ingelheim (Ridgefield, CT)
- …group, the successful Principal/Senior Principal Scientist will design and implement mechanistic PK / PD and quantitative systems pharmacology models in support of ... highly innovative pre-clinical NBE portfolio. This scientist will represent the PK / PD modeling discipline on multi-disciplinary drug discovery project teams… more
- AbbVie (North Chicago, IL)
- …will establish innovative translational modeling approaches, such as mechanistic pharmacokinetic / pharmacodynamic ( PK / PD ) and toxicokinetic/toxicodynamic ... pharmacology, and preclinical safety (PCS), to develop and execute QTAS and PK / PD strategies necessary to facilitate the advancement of our pipeline. Purpose… more
- AbbVie (South San Francisco, CA)
- …The candidate will establish innovative translational modeling approaches, such as mechanistic PK / PD or systems modeling, across disease and therapeutic areas, ... clinical pharmacology, and other stakeholders, to develop and execute QTAS and PK / PD strategies necessary to facilitate the advancement of our pipeline. Key… more
- Lilly (Indianapolis, IN)
- …advance the science in this subject area, we are seeking a scientific director who will lead a group of quantitative systems pharmacology (QSP) computational ... and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a… more
