- Generation Bio (Cambridge, MA)
- …leveraging its T cell selective cell-targeted lipid nanoparticle (ctLNP) to deliver siRNA in vivo, enabling modulation of T cell activity that causes inflammation ... By selectively modulating T cells that drive disease pathology, ctLNP- siRNA therapeutics could potently block target function with sequence-level specificity… more
- BioSpace (Redwood City, CA)
- …technologies and ensuring robust, scalable, and cost-effective manufacturing processes for therapeutic siRNA assets. If any of the below describes you, we would love ... to meet you! Possess a passion for being part of the therapeutic community helping bring cutting edge treatments to patients in need. Enjoys collaboration across different functional groups to get a holistic understanding of process development along with… more
- Alloy Therapeutics (Waltham, MA)
- …who have recently graduated and whose research topic has been in the siRNA or CRISPR/Editing fields and could have one year of postdoctoral experience. Our ... research involves experiments with RNA biology, Oligonucleotide chemistry, Antisense and siRNA designs, Gene editing and mRNA Therapeutics. How You'll Drive Impact +… more
- University of Michigan (Ann Arbor, MI)
- …be pivotal in building our cutting-edge oligo synthesis platform - enabling ASO, siRNA , and CRISPR guide RNA generation to support translational science on campus ... setting, withdirect experience in oligonucleotide synthesis and purification (eg, ASO, siRNA , gRNA), preferably using automated synthesizers such as Dr. Oligo. +… more
- J&J Family of Companies (San Diego, CA)
- …Areas of Study-oligonucleotide chemistry and analytics/oligonucleotide biology with focus in siRNA + **Required Years of Related Experience:** 0-1 + Hands-on ... experience in ASO and/or siRNA chemistry, including synthesis, modification, and conjugation + Strong...monomers, raw materials, and oligonucleotide synthesis reactions related to siRNA + A proven track record of success as… more
- University of Michigan (Ann Arbor, MI)
- …will be pivotal in building our cutting-edge oligo synthesis platform?enabling ASO, siRNA , and CRISPR guide RNA generation to support translational science on campus ... discipline + Direct experience in oligonucleotide synthesis and purification (eg, ASO, siRNA , gRNA), preferably using automated synthesizers such as Dr. Oligo. +… more
- Texas A&M University System (Bryan, TX)
- …gene editing and CRISPRi/a-based transcriptional modulation + RNA interference ( siRNA /shRNA) assays for gene knockdown studies + RNA immunoprecipitation (RIP) ... and cross-linking immunoprecipitation (CLIP) assays + Quantitative real-time PCR (qRT-PCR), RT-PCR, and Northern blotting + Western blotting, immunoprecipitation (IP), and co-immunoprecipitation (co-IP) for protein analysis and interaction studies + Microscopy… more
- J&J Family of Companies (San Diego, CA)
- …modes) to support projects of multiple drug modalities such as small molecules, siRNA , PROTAC, Bispecific antibody, and CAR T-cell therapy. + De novo methodology ... design and productive implementation, for studies using mass spectrometry, to ensure timely delivery. + Initiate and perform hypothesis-driven investigation into mechanisms of toxicities. + Work closely and be an avid contributor within the multi-disciplinary… more
- Takeda Pharmaceuticals (Boston, MA)
- …cell-based and biochemical assays; required skills include gene editing (CRISPR or siRNA ), cell culture including work with primary immune cells, cytokine analysis ... (AlphaLISA, MSD, ELISA), and flow cytometry etc. + Experience developing in vitro assays characterizing small molecule and biologics potency and mechanism of action + Excellent written and verbal communication skills and the ability to work effectively in a… more
- University of Maryland, Baltimore (Baltimore, MD)
- …culture and patient-derived xenografts), and state-of-the-art functional technologies (CRISPR, siRNA , shRNA, and other gene manipulation techniques). Our work is ... published in top-tier journals - Cancer Research, Clinical Cancer Research, Nature Communications, PNAS, NAR, and others. The Gaykalova Lab is looking for an enthusiastic, highly-motivated postdoc, interested in cancer epigenetics. In particular, a qualified… more
- J&J Family of Companies (Spring House, PA)
- …is required. + Expert knowledge and experience in multiple modalities (eg siRNA , ADC, small molecules) therapeutic discovery and development + Deep scientific track ... record of expertise in preclinical drug development, as well as the ability to present externally should be demonstrated from a drug development experience, examples of presenting to senior leadership, and external eminence. + A record of success in partnering… more
- UTMB Health (Galveston, TX)
- …related field. Basic research experiences/skills are required, including siRNA , immunoprecipitation, immunoblotting, cell culture, ELISA, and/or flow cytometric ... analysis. The successful candidate would be expected to perform experiments independently under PI's supervision, organize data, draft manuscript, and present research findings in scientific meetings and conferences. **MINIMUM QUALIFICATIONS:** Ph.D., MD or… more
- US Tech Solutions (South San Francisco, CA)
- …affinity purification of therapeutic proteins (including but not limited to antibody- siRNA conjugates, and fusion proteins) from biological matrices. + Analyze data ... and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks. + Facilitate assay optimization and implementation to ensure laboratory capacity and data quality. + Communicate data interpretation internally and… more
- University of Miami (Miami, FL)
- …DNA gel electrophoresis, Northern blotting, Western blotting, Southern Blotting, siRNA /DNA transfections, are preferred. + Work related knowledge in Direct ... PCR, Phusion, and Tropism Assays, HIV virus production, and envelope cloning for HIV. + Collaborate with other employees, good organizational skills, and excellent computer skills required. + Excellent English language skills (both verbal and written)… more
- Lilly (Indianapolis, IN)
- …supporting biotransformation/bioanalysis of new modalities (ie ADC's, peptides, RNA, siRNA , ARC's). + Strong leadership, communication, and interpersonal skills. + ... Experience with regulatory guidance(s) for drug development. + Experience managing scientific teams + Deep understanding of biotransformation, and drug metabolism impact on moving compounds from Discovery though IND to NDA Lilly is dedicated to helping… more
- Emory Healthcare/Emory University (Atlanta, GA)
- …interaction studies, HPLC operation, etc.). + Molecular biology and experimental genetics ( siRNA , CRISPR, PCR, DNA cloning, etc.). + DNA sequence analysis (Snapgene, ... Geneious or other DNA analysis tools). + Experience analyzing large datasets. NOTE: Position tasks are required to be performed in-person at an Emory University location; working remote is not an option. Emory reserves the right to change this status with… more
- Emory Healthcare/Emory University (Atlanta, GA)
- …interaction studies, HPLC operation, etc.). + Molecular biology and experimental genetics ( siRNA , CRISPR, PCR, DNA cloning, etc.). + DNA sequence analysis (Snapgene, ... Geneious or other DNA analysis tools). + Experience analyzing large datasets. NOTE: Position tasks are required to be performed in-person at an Emory University location; working remote is not an option. Emory reserves the right to change this status with… more
- Mayo Clinic (Jacksonville, FL)
- …biology with translation into RNA therapeutics including but not limited to ASO, siRNA , aptamers, mRNA therapeutics. The candidate is expected to have a strong track ... record of extramural funding, high impact publications, as well as a proven record of collaborative team science endeavors as exemplified by leading multi-institutional grants and/or inter-disciplinary programs in the area of RNA biology, therapeutics and… more
- Emory Healthcare/Emory University (Atlanta, GA)
- …interaction studies, HPLC operation, etc.) + Molecular biology and experimental genetics ( siRNA , CRISPR, PCR, DNA cloning, etc.) + DNA sequence analysis (Snapgene, ... Geneious or other DNA analysis tools) + Experience analyzing large datasets **The Gordon Lab pioneers advanced mass spectrometry, experimental genetics, and** **computational approaches to map biochemical networks and functional pathways,** **and leverages… more
- Wayne State University (Detroit, MI)
- …experience with cell culture, molecular biology techniques (PCR, cloning, mutagenesis, siRNA , ChIP), biochemistry (co-IP, westerns). - Prior experience in cancer ... research will be a plus but is not essential School/College/Division: H06 - School of Medicine Primary department: H0632 - Oncology Employment type: + Regular Employee + Job type: Fractional Time + Job category: Research Funding/salary information: +… more
