- Merck & Co. (Rahway, NJ)
- …analysis ready structures from varied data sourcesCreate modeling-ready datasets by integrating PK , PD and covariate dataProduce tables and graphics for ... Job DescriptionIn BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our...expertise with clinical endpoint data (efficacy and safety) and pharmacokinetic data (raw concentration data, derived PK … more
- Merck & Co. (Rahway, NJ)
- …programming deliverables for global stakeholders in Early Development Statistics and PK / PD Modeling and Simulation spanning all therapeutic areas except ... programming expertise with clinical endpoint data (efficacy and safety) and pharmacokinetic data (raw concentration data, derived PK parameters).Significant… more
- Children's Hospital Los Angeles (Los Angeles, CA)
- …Matters.** **Overview** **Schedule:** Monday-Friday; Days **Purpose Statement/Position Summary:** The research scientist will be responsible for supporting ... infection model (HFIM) to mimic human pharmacokinetics and pharmacodynamics ( PK - PD ) in vitro to improve dosing strategies...experience is not required. Reporting to the directors, the Research Scientist will: 1. Develop, validate, and… more
- AbbVie (Irvine, CA)
- …in patents and manuscripts. The LDTS group at AbbVie, is seeking a Principal Research Scientist - Modeling and Simulation. As a member of multidisciplinary ... modeling and simulation expert with matrix project teams. Specific responsibilities include: + Apply PK and PK / PD modeling/simulation to guide the design and… more
- Boehringer Ingelheim (Ridgefield, CT)
- …aspects of cancer immune reprogramming is a must. + Experience with efficacy and pharmacokinetic /pharmacodynamics ( PK / PD ) and biomarker studies is a plus. + ... candidate selection, as well as to explore MOA and PD biomarkers for both large molecules and small molecule...Switzerland and the USA including occasional travel to global research sites. **Senior Principal Scientist :** + Ph.D.… more
- Amgen (South San Francisco, CA)
- …Quantitative Translational and Clinical Pharmacology approaches - such as Pharmacokinetic / Pharmacodynamic ( PK / PD ) modeling, Mechanistic-Physiologically ... Based Pharmacokinetic (M-PBPK) modeling, Mechanistic-PBPK- Pharmacodynamic (M-PBPK- PD ) modeling, Quantitative Systems Pharmacology (QSP) modeling - integrated… more
- Bristol Myers Squibb (Cambridge, MA)
- …modalities. **Position Summary:** We are seeking an accomplished and visionary Senior Principal Scientist or Associate Director to lead our Immunology in vivo ... team, providing scientific and strategic direction. + Identify and implement appropriate PK / PD and disease models to support clinical candidate selection, human… more
- Bristol Myers Squibb (Cambridge, MA)
- …ADME/ PK skills such as in vitro ADME, in vivo ADME, biotransformation, PK / PD , or physiologically based pharmacokinetic modeling (PBPK) to impact project ... lives. Read more: careers.bms.com/working-with-us . Job Requisition: Senior Principal Scientist , Development DMPK Challenging. Meaningful. Life-changing. Those aren't words… more
- Boehringer Ingelheim (Ridgefield, CT)
- …strong background in Toxicokinetics (TK) as well as mechanistic pharmacokinetics ( PK ) investigation to join the NonClinical Pharmacokinetic / Biodistribution ... research , nonclinical safety, and clinical pharmacology teams to fully understand drug PK / PD . In addition, the candidate will be responsible for managing and… more
- Bristol Myers Squibb (Cambridge, MA)
- …as part of the lead selection process, utilizing strong foundational knowledge of building PK , PD , BioD and efficacy relationship in vivo and employ innovative ... ability to independently develop focused in vivo strategies and utilizing PK / PD /efficacy data to drive discovery, optimization, and characterization of… more
- Merck (West Point, PA)
- …discovery efforts providing an integrated understanding of DMPK properties, pharmacokinetics/pharmacodynamics ( PK / PD ), and drug interaction (DDI) risk of novel ... to enable translational modeling and simulation to support dose selection, design of PK / PD and safety assessment studies, and dose justifications for preclinical… more
- Merck (North Wales, PA)
- …analysis ready structures from varied data sources + Create modeling-ready datasets by integrating PK , PD and covariate data + Produce tables and graphics for ... **Job Description** In BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our...expertise with clinical endpoint data (efficacy and safety) and pharmacokinetic data (raw concentration data, derived PK … more
- Amgen (South San Francisco, CA)
- …dosage regimens and study designs. + Contributes to the analysis of in-vitro and pre-clinical PK / PD data for selection of first in humans (FIH) dose levels and ... area(s) and handling life science datasets is preferred + Experience in PK / PD modeling and population-based analyses/simulations with established track-record of… more
- Merck (Rahway, NJ)
- …programming deliverables for global stakeholders in Early Development Statistics and PK / PD Modeling and Simulation spanning all therapeutic areas except ... possess programming expertise with clinical endpoint data (efficacy and safety) and pharmacokinetic data (raw concentration data, derived PK parameters). +… more
- Bristol Myers Squibb (Princeton, NJ)
- …+ Perform in vivo and in vitro/ex vivo studies to define pharmacodynamic / pharmacokinetic relationships and characterize and develop models of disease relevant ... personal lives. Read more: careers.bms.com/working-with-us . The Immunology and Cardiovascular Thematic Research Center (ICV TRC) at BMS is one of the fundamental … more
- Pfizer (Groton, CT)
- …abstracts, and presentations. + May interface with safety sciences, statistics, PK / PD , regulatory, outcomes research , development operations, other ... innovative clinical study designs and high-quality trial execution with Oncology Research Development (ORD). + Participate in safety assessment and interpretation of… more
- Bristol Myers Squibb (Madison, NJ)
- …of the disease area(s), KOLs, indication(s), compound(s) under study (including MOA, PK / PD , biomarker & safety profile) + Proficient critical thinking, problem ... personal lives. Read more: careers.bms.com/working-with-us . The Senior Clinical Scientist reports through the Clinical Science function which provides scientific… more
- Amgen (South San Francisco, CA)
- …ADME/ PK skills such as in vitro ADME, in vivo ADME, biotransformation, PK / PD , or physiologically-based pharmacokinetic modeling (PBPK) to impact project ... will characterize the absorption, distribution, metabolism, excretion (ADME) and pharmacokinetic ( PK ) properties of SM therapeutic drug...+ Expertise with in vitro ADME, in vivo ADME, PK / PD or PBPK + Experience in supporting… more
- Lilly (San Diego, CA)
- …exceptional physician scientist to join our Immunology team as Medical Director , Early Clinical Development. This role is designed for a clinical translational ... endpoints, biomarker strategies, precision medicine approaches, clinical pharmacology, and pharmacokinetic / pharmacodynamic modelingPrevious experience in autoimmune therapeutic areas… more
- ICON Clinical Research (Lenexa, KS)
- …(ligand binding experience required)** + **Ligand binding assays** + **ELISA, ECLIA** + ** PK , PD , and immunogenicity** + **Usage of relevant software (eg SoftMax ... Office-based ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving… more
