- Takeda Pharmaceuticals (Boston, MA)
- …Biology and Automation to manage and enhance internal capabilities in crystallography and cryoEM, contribute to computational capabilities and engage with external ... to oversee design, execution and interpretations of structural biology experiments ( crystallography and cryoEM) using both internal and external capabilities for all… more
- Dana-Farber Cancer Institute (Boston, MA)
- …signal transduction pathways. + Utilize structural methods such as X-ray crystallography , cryo-EM, or NMR for protein structure elucidation. + Perform protein ... in protein expression and purification. + Experience with structural methods (X-ray crystallography , cryo-EM, or NMR) is highly desirable. + Proficiency in basic… more
- Lilly (San Diego, CA)
- …cutting-edge tools, to extract insight from diverse experiments-SPR, NMR, crystallography , cryo-EM, virtual screens-and convert them into actionable hypotheses. Your ... binding analysis and Molecular Dynamics (MD). + Experience in X-ray crystallography and cryo-EM data collection, processing, protein model and ligand building.… more
- Lilly (San Diego, CA)
- …techniques to accelerate generation of high-quality reagents for X-ray crystallography and cryogenic electron microscopy (cryo-EM) studies. Determine structures and ... protein engineering, protein biochemistry, and protein structure determination by X-ray crystallography or cryo-EM; 2 years of experience with construct design,… more
- J&J Family of Companies (Spring House, PA)
- …with computational chemistry methods and biophysical techniques such as X-ray crystallography and macromolecular NMR is preferred + Ability to integrate multiple ... R&D disciplines into a successful project plan is required + Strong problem-solving skills for developing creative, innovative solutions, and meeting project objectives are required + Demonstrated influence, negotiation, and conflict resolution skills,… more
- AbbVie (Worcester, MA)
- …biophysical, and structural methods, such as SEC, MS, HDX-MS, X-ray crystallography , DSF, DLS, etc. + Experience with biologics, monoclonal antibodies and/or ... protein therapeutics. + Excellent organizational skills with the capacity to manage multiple projects and tasks simultaneously within timelines. + Goal-oriented team player with excellent verbal and written communication skills and a strong can-do attitude and… more
- AbbVie (North Chicago, IL)
- …AI/ML methodologies into structural biology research. Hands-on experience with X-ray crystallography and cryo-EM data processing and structure analysis is highly ... preferred. This role offers the opportunity to work within a centralized, multidisciplinary team, supporting global Discovery Research across AbbVie's portfolio. Key Responsibilities: + Lead development and integration of AI/ML methodologies to enhance… more
- University of Florida (Palm Beach, FL)
- …biology, protein expression, purification, biochemistry, cryo-EM, and protein crystallography . Expected Salary: Commensurate with experience. Minimum Requirements: ... High school students who are dual enrolled in college courses will be considered. Ability to work 15-20 hours per week. Preferred Qualifications: Minimum grade point average (GPA) of 3.5. Candidate should be a student enrolled in a bachelor's program in an… more
- Rockefeller University (New York, NY)
- …a multidisciplinary approach that combines structural biology (X-ray crystallography and cry-EM) with biochemical,genetic,and cell biology techniques. Structural ... and functional studies of early ribosome assembly intermediates are complemented by the biochemical characterization of multi-protein complexes. Overview The ideal candidate will be working closely with the PI and a small group of researchers within the lab… more
- Gilead Sciences, Inc. (Foster City, CA)
- …The Structural Biology Group is well equipped with an advanced X-ray crystallography laboratory and a state-of-the-art cryo-EM facility hosting a Glacios and a ... Krios G4 microscopes. The group provides critical structural information to elucidate the mechanism of action and to facilitate lead molecule optimization, and supports diverse drug discovery projects spanning virology, inflammation, and oncology. This postdoc… more
- Argonne National Laboratory (Lemont, IL)
- …coherent diDraction imaging or x-ray microscopy methods. + Knowledge of crystallography . + Experience with molecular modeling of crystals, dislocation dynamics, and ... defect analysis, linking atomic-scale simulations to macroscopic properties. + Familiarity or interest in machine learning methods and computing frameworks such as PyTorch and TensorFlow. + Experience with high-performance computing and/or scientific workflow.… more
- Boston College (Chestnut Hill, MA)
- …a nanofabrication, bioinformatics server, mass spectrometry, flowcytometry, NMR and X-ray crystallography facility. The following are examples of typical duties, but ... other duties may also be assigned. + Development of the research project including planning and designing experiments, data analysis. + Presentation of project results at meetings and seminars. + Publication of high-quality research articles. + May be… more
- Mount Sinai Health System (New York, NY)
- …and structure-based drug design based on known ligands and X-ray crystallography co-crystal data available from collaborator labs. Preparation, purification and ... characterization of compounds in chemistry laboratory; documentation of all experiments in electronic lab notebooks (ELN) including written, publication quality, experimental procedures. Operation and maintenance of laboratory instruments - HPLC and LC-MS for… more
- Mount Sinai Health System (New York, NY)
- …hands-on experience with cutting-edge techniques like **cryo-EM** and **X-ray crystallography ** in a collaborative environment. This is an incredible opportunity ... for recent graduates to enhance their skills and contribute to high-impact projects. Ready to make a difference? Apply now and be a part of our team! **Qualifications** **How to apply:** Please submit a single PDF containing your cover letter, curriculum… more
- UTMB Health (Galveston, TX)
- …purification, molecular biology, solution biophysics, NMR, X-ray crystallography , cryo-electron microscopy, bioinformatics, and computational chemistry ... (seehttp://www.utmb.edu/core). The University of Texas Medical Branch at Galveston (UTMB) is a major academic health sciences center located on the Texas Gulf Coast. Galveston has a mild, sub-tropical climate with outstanding recreational opportunities. The… more
- Argonne National Laboratory (Lemont, IL)
- …+ Experience with Python and/or C/C++ Knowledge of diffraction theory, crystallography , and approaches to advanced analysis including structural refinement and ... modeling + Skill in oral and written communication of scientific results and experimental plans + Ability to work well in a team environment + Flexibility and fast adaptation to new situations + Ability to model Argonne's core values of impact, safety,… more
- Cedars-Sinai (Los Angeles, CA)
- …other techniques will be applied, such as structure determination by X-ray crystallography and/or more advanced cell-based methodology in use in the lab ... (CRISPR/Cas9, flow cytometry, microscopy, gene knock-out/knock-down, migration assays, etc.). The laboratory has a well-established supervision system for undergrads and master students. The intern will interact daily with the direct supervisor and… more
- Wayne State University (Detroit, MI)
- …E. Coli - Protein Crystallization and solution of structure through x-ray crystallography - Computational docking, modeling, and virtual screening - Optimize FRET ... assays to test lead compounds - Determine enzyme kinetic parameters (Km, Ki, kinact determination, etc.) - Protein thermodynamic studies - Optimize lead compounds with medicinal chemists - Public speaking - Mentor/guide graduate students - Manage lab inventory… more
- University of Michigan (Ann Arbor, MI)
- …in developing correlative cryo-ET workflows, and combining X-ray crystallography , single-particle cryo-EM, biochemistry and biophysics to dissect protein-nucleic ... acid systems. **Mission Statement** Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in… more
- University of Florida (Palm Beach, FL)
- …expression, purification, and biochemistry, and cryogenic electron microscopy, and protein crystallography . The laboratory has access to a large cast of outstanding ... Cores that facilitate basic research and drug development. The unique infrastructure includes the application of unique chemical, genomic, proteomic, informatics, and high-throughput screening and engineering tools for the discovery of novel biomolecules.… more
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