- Merck & Co. (South San Francisco, CA)
- …Translational Medicine is seeking applicants for a Senior Scientist position, In Vivo Imaging, available at our South San Francisco, California research facility. ... will lead efforts to implement and validate novel imaging methods in in vivo animal models of human diseases across multiple imaging platforms (eg optical, CT,… more
- Cedars-Sinai (Los Angeles, CA)
- …Cancer Center. Our research group has an established track record in the study of metabolic pathways using in vivo and ex vivo multi-omics approaches, ... unique opportunity within the research group is to establish in vivo mouse models to study metabolic changes in the heart during cancer. Currently, a particular… more
- Merck (South San Francisco, CA)
- …Translational Medicine is seeking applicants for a Senior Scientist position, In Vivo Imaging, available at our South San Francisco, California research facility. ... trials. **Primary Responsibilities:** + Discover and development of novel in vivo imaging-based biomarkers to support drug discovery and development + Coordinate… more
- Bristol Myers Squibb (Princeton, NJ)
- …on metabolite profiling and characterization of drug candidates in vitro and in vivo to understand metabolic pathways to support drug discovery and development. ... oversight of cold and radiolabeled in vitro and in vivo preclinical and clinical biotransformation studies for small molecules...product profiles, and to integrate in vitro and in vivo drug metabolism and disposition data for team presentations.… more
- Gilead Sciences, Inc. (Foster City, CA)
- …on metabolite profiling and characterization of those compounds in vitro and in vivo to understand metabolic pathways to support drug discovery and development. ... strategies to achieve target product profiles, integrate in vitro and in vivo drug disposition data, interpretation, and give presentations to teams. + Provide… more
- UCLA Fielding School of Public Health (Los Angeles, CA)
- …such spectral flow cytometry, proteomic assays, confocal microscopy, and in vivo imaging in conditional knockout mouse models; 2) performing unbiased screens ... and how these affect cellular responses to stress; and, 4) developing new ex vivo models from human lung specimens for investigating the pathogenesis of lung injury… more
- Charles River Laboratories (Collegeville, PA)
- …in a laboratory animal facility performing directly related services, including in vivo research. + Associate's degree in animal science or related field plus ... working in a laboratory animal facility performing directly related services, including in vivo research. + High School Diploma and at least 4 years' experience… more
- University of Southern California (Los Angeles, CA)
- …researcher who is interested in the field of liver disease (eg metabolic liver disease, viral hepatitis, liver inflammation, and hepatic immunity). The candidate ... is expected to have significant experience with in vitro and vivo experiments, including but not limited to primary cell isolation/culture, general molecular… more
- University of Utah (Salt Lake City, UT)
- …We are interested in candidates who are passionate about inherited metabolic disorders, specifically those involving congenital disorders of glycosylation ( CDG ... candidates with documented research skills and experience combining innovative in vivo and in vitro approaches for investigating pathophysiology and developing… more
- Mount Sinai Health System (New York, NY)
- …to develop efficient and safe interventions for preventing and treating metabolic diseases. Her recent publications include Cell Metabolism, Journal of Hepatology, ... technologies used in the lab include transgenic mouse models, human genetics, metabolic studies, stem cell biology, next generation sequencing, and a variety of… more
- Florida Atlantic University (Jupiter, FL)
- …and tissue imaging techniques to study mechanisms of neuronal dysfunction. In Vivo Studies: Conducting research using mouse models to explore mechanisms of disease ... progression. Experimental Procedures: Cell culture and analysis of metabolic and functional state; cell imaging; iPSC-derived brain cells; western blots;… more
- University of Michigan (Ann Arbor, MI)
- …of adipose tissue biology with the goal of developing novel therapy for metabolic diseases including diabetes. We utilize sophisticated 2D and 3D human and murine ... analysis, bulk and single cell RNA sequencing, and murine in vivo adipocyte/adipose tissue transplant/xenograft models to study adipocyte-matrix interactions in… more
- Amgen (Thousand Oaks, CA)
- …platforms **Cross-Functional Collaboration** : Partner closely with in vivo pharmacologists, protein biochemists, structural biologists, medicinal chemists, ... and/or related areas. + Deep technical expertise in signal transduction, metabolic regulation, and/or in vitro pharmacology. + Demonstrated creativity and scientific… more
- The County of Los Angeles (Los Angeles, CA)
- …and our communities by providing extraordinary care. DEFINITION: Performs advanced metabolic and advanced dynamic radioisotope scanning tests and associated wet ... Adapts new nuclear medicine procedures for routine use. + Performs metabolic tests including ferrokinetic, albumin turnovers calcium absorption, protein turnover,… more
- Gilead Sciences, Inc. (Foster City, CA)
- …quantitative roles of enzymes in the disposition of those drug candidates ( metabolic phenotyping). More broadly, the scientist is expected to integrate this ... to determine the roles of various enzymes in the metabolic profiles of those compounds. + Serve as a...achieve target product profiles, integrate in vitro and in vivo drug disposition data, interpretation, and give presentations to… more
- Mount Sinai Health System (New York, NY)
- …to residual cardiovascular disease risk. Using a combination of in vivo physiology, molecular biology, stable isotope tracer methodology and integrative multi-omics, ... we aim to define the critical metabolic pathways that underlie atherosclerotic plaque progression and vulnerability. We are currently focused on two integrated areas… more
- Amgen (South San Francisco, CA)
- …areas including Oncology, Inflammation, General Medicine, and Cardiovascular or Metabolic diseases The successful candidate will bring expertise in high-dimensional ... genomics analysis and surfaceome-based target discovery projects using in vitro and ex vivo models (cell lines, organoids, tissues). + Assist to develop and apply… more
- Dana-Farber Cancer Institute (Boston, MA)
- …and chemoproteomics studies + Help develop and apply biochemical, biophysical, and metabolic stability assays + Screen compounds; analyze and interpret data + Apply ... iterative design of optimized chemical probes suitable for cellular and in vivo pharmacological studies + Maintain accurate lab records and documentation +… more
- University of Pennsylvania (Philadelphia, PA)
- …oligodendrocytes, imaging and analysis of oligodendrocyte in vitro and in vivo using fluorescence, confocal, live cell microscopy, knowledge of cellular organellar ... Division of Child Neurology with basic neuroscientists, developmental pediatrics, metabolic medicine, psychiatry, cardiology, critical pediatric and neonatal medicine,… more
- Otsuka America Pharmaceutical Inc. (Boston, MA)
- …to a team of translational scientists developing primary human cell and ex vivo systems to support program hypotheses and biomarker discovery. + Support regulatory ... + Strong background in immunology and rheumatological disease; knowledge of nephrology or metabolic disease is a plus. + Proven track record in biomarker strategy… more
