- Cedars-Sinai (Los Angeles, CA)
- …Cancer Center. Our research group has an established track record in the study of metabolic pathways using in vivo and ex vivo multi-omics approaches, ... unique opportunity within the research group is to establish in vivo mouse models to study metabolic changes in the heart during cancer. Currently, a particular… more
- Charles River Laboratories (South San Francisco, CA)
- …**Job Summary** We are seeking an experienced **Research Associate III - In Vivo ** to join our **Insourcing Solutions team** , located in **South San Francisco, ... CA** . As the **Research Associate III - In Vivo ** , you will be responsible for performing required...of mouse physiologic and behavioral assays including grip strength, metabolic cages, glucose/insulin tolerance + Necropsy and tissue collection… more
- J&J Family of Companies (Spring House, PA)
- …(domestic and international), defined by business needs **Preferred:** * Large pharma in vivo pharmacology * Publications record in metabolic and CV indications ... **We are searching for the best talent for a Sr. Scientist, In vivo Pharmacology Aging & Metabolism to be in Spring House, PA.** **Purpose:** The… more
- WuXi AppTec (San Diego, CA)
- **Overview** HD Biosciences, a WuXi AppTec company, seeks a Director - In Vivo Pharmacology to manage team and project operations. The candidate must provide ... objectives. This key position will report directly to the head of the In Vivo Pharmacology Department. **Responsibilities** * Act as a Subject Matter Expert (SME) in… more
- Gilead Sciences, Inc. (Foster City, CA)
- …on metabolite profiling and characterization of those compounds in vitro and in vivo to understand metabolic pathways to support drug discovery and development. ... strategies to achieve target product profiles, integrate in vitro and in vivo drug disposition data, interpretation, and give presentations to teams. + Provide… more
- UCLA Fielding School of Public Health (Los Angeles, CA)
- …such spectral flow cytometry, proteomic assays, confocal microscopy, and in vivo imaging in conditional knockout mouse models; 2) performing unbiased screens ... and how these affect cellular responses to stress; and, 4) developing new ex vivo models from human lung specimens for investigating the pathogenesis of lung injury… more
- University of Southern California (Los Angeles, CA)
- …researcher who is interested in the field of liver disease (eg metabolic liver disease, viral hepatitis, liver inflammation, and hepatic immunity). The candidate ... is expected to have significant experience with in vitro and vivo experiments, including but not limited to primary cell isolation/culture, general molecular… more
- University of Utah (Salt Lake City, UT)
- …We are interested in candidates who are passionate about inherited metabolic disorders, specifically those involving congenital disorders of glycosylation ( CDG ... candidates with documented research skills and experience combining innovative in vivo and in vitro approaches for investigating pathophysiology and developing… more
- Merck (South San Francisco, CA)
- …in project teams across multiple therapeutic areas, including Oncology, Cardiovascular metabolic disease, and Immunology. The candidate will develop a project team ... of team-specific PDMB workflow. + Design and execute in vitro and in vivo mechanistic and translational studies to evaluate the pharmacokinetic and metabolic … more
- Merck (South San Francisco, CA)
- …pharmacologist with extensive drug discovery expertise in cardiovascular and metabolic diseases to join our Quantitative Biosciences (Pharmacology) department. The ... responsible for the design, execution, and interpretation of complex in vitro/ex vivo assays as well as mechanistic experimentation to advance drug discovery from… more
- Georgetown Univerisity (Washington, DC)
- …quantitation. The candidate will also assist in developing pipeline for metabolic model development, modelling, stoichiometric analysis of metabolic flux. ... proteomics, metabolomics (including stable isotope based in vitro and in vivo metabolomics) and mass spectrometry-based profiling. MSR is a highly productive… more
- Mount Sinai Health System (New York, NY)
- …to develop efficient and safe interventions for preventing and treating metabolic diseases. Her recent publications include Cell Metabolism, Journal of Hepatology, ... technologies used in the lab include transgenic mouse models, human genetics, metabolic studies, stem cell biology, next generation sequencing, and a variety of… more
- MD Anderson Cancer Center (Houston, TX)
- …metabolism. The lab employs advanced biochemical technologies to explore metabolic alterations in health and disease. Techniques include proteomics, metabolomics, ... enzymology, metabolic imaging, and isotope tracing both in vitro and in vivo . *LEARNING OBJECTIVES* * Gain hands-on experience in metabolism-related research and… more
- The County of Los Angeles (Los Angeles, CA)
- …and our communities by providing extraordinary care. DEFINITION: Performs advanced metabolic and advanced dynamic radioisotope scanning tests and associated wet ... Adapts new nuclear medicine procedures for routine use. + Performs metabolic tests including ferrokinetic, albumin turnovers calcium absorption, protein turnover,… more
- Gilead Sciences, Inc. (Foster City, CA)
- …quantitative roles of enzymes in the disposition of those drug candidates ( metabolic phenotyping). More broadly, the scientist is expected to integrate this ... to determine the roles of various enzymes in the metabolic profiles of those compounds. + Serve as a...achieve target product profiles, integrate in vitro and in vivo drug disposition data, interpretation, and give presentations to… more
- Mount Sinai Health System (New York, NY)
- …to residual cardiovascular disease risk. Using a combination of in vivo physiology, molecular biology, stable isotope tracer methodology and integrative multi-omics, ... we aim to define the critical metabolic pathways that underlie atherosclerotic plaque progression and vulnerability. We are currently focused on two integrated areas… more
- University of Utah (Salt Lake City, UT)
- …how glycosaminoglycans, such as heparan sulfate, regulate signaling pathways involved in metabolic homeostasis and cardiovascular disease. Using a combination of in ... vivo mouse models, cell-based systems, and biochemical approaches, we aim to uncover the molecular mechanisms underlying lipid metabolism, inflammation, and insulin… more
- MD Anderson Cancer Center (Houston, TX)
- …Communications 2024; Science Translational Medicine 2025, in press) and immune- metabolic crosstalk in liver regeneration (Nature Metabolism 2024). Our research ... RNA-binding proteins in homeostasis and metastasis * Perform next generation in vivo forward genetic screens to identify novel metastasis drivers * Investigate new… more
- University of Pennsylvania (Philadelphia, PA)
- …oligodendrocytes, imaging and analysis of oligodendrocyte in vitro and in vivo using fluorescence, confocal, live cell microscopy, knowledge of cellular organellar ... Division of Child Neurology with basic neuroscientists, developmental pediatrics, metabolic medicine, psychiatry, cardiology, critical pediatric and neonatal medicine,… more
- Mount Sinai Health System (New York, NY)
- …non-coding RNAs, stable-isotope-labeling mass spectrometry, in vitro and in vivo imaging, live imaging of exosomes, microfluidics isolation, bionanotechnology, ... flow cytometry, histology of the heart, echocardiography, MTT assay to assess metabolic activity, Western blot, PCR, RNA sequencing and data analysis, exosomes… more