• Principal Scientist I / II,…

    Schrodinger (Cambridge, MA)
    We're looking to hire a ** Principal Scientist in Medicinal Chemistry ** to join us in our mission to discover and develop drugs that improve human health ... qualifications. **Who will love this job:** + A passionate scientist with a robust background in structure-based drug design...chemistry + At least four years of drug discovery experience in a pharmaceutical and/or biotech setting +… more
    Schrodinger (10/11/25)
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  • Senior Principal Scientist

    Schrodinger (NY)
    We're looking to hire a **Senior Principal Scientist ** or **Director of Medicinal Chemistry ** to join us in our mission to discover and develop drugs that ... qualifications. **Who will love this job:** + A passionate scientist with a robust background in structure-based drug design...chemistry + At least eight years of drug discovery experience in a pharmaceutical and/or biotech setting +… more
    Schrodinger (10/11/25)
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  • Principal Scientist , Computational…

    Frontier Medicines (Boston, MA)
    …Medicines is seeking a highly motivated individual to fill the position of Principal Scientist , Computational Chemistry . The successful candidate will play ... a leading role in developing medicinal chemistry optimization strategies for key drug discovery ...medicinal chemistry optimization strategies for key drug discovery programs. This individual will review experimental results, develop… more
    Frontier Medicines (11/04/25)
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  • Principal Scientist , Drug…

    Merck (Rahway, NJ)
    **Job Description** The Principal Scientist , Drug Discovery in our Research and Development Department will be responsible for identifying new molecular ... resources for the necessary research work (Medicinal and Process Chemistry , in vitro Pharmacology, Pharmacokinetics, Disease Models, Formulation Development, Safety… more
    Merck (12/18/25)
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  • Senior / Principal Scientist

    Boehringer Ingelheim (Ridgefield, CT)
    …innovation in small molecule development. The Principal Scientist /Sr. Scientist will lead efforts in solid-state chemistry and API engineering, focusing ... **Description** Boehringer Ingelheim is currently seeking a Senior or Principal Scientist to support our Material and Analytical Sciences team to join our… more
    Boehringer Ingelheim (11/20/25)
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  • Senior Principal Scientist , Pre

    Pfizer (San Diego County, CA)
    **ROLE SUMMARY** This Senior Principal Scientist position will be a strong scientific and leadership role within the Early Formulation Science and Drug Delivery ... and drug delivery systems design + Integrates pharmaceutics, physical organic chemistry , biophysical chemistry , supramolecular chemistry , materials science,… more
    Pfizer (11/19/25)
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  • Associate Principal Scientist

    Merck (South San Francisco, CA)
    …drug conjugates, and novel modality discovery and development pipeline. The Associate Principal Scientist will be primarily discovery team-facing and is ... SSF Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) group is seeking an Associate Principal Scientist to contribute to our Company's biologics,… more
    Merck (12/04/25)
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  • Principal Scientist , Drug…

    Merck (West Point, PA)
    scientist for the Drug Metabolism and Pharmacokinetics (DMPK) group. The Principal Scientist will be a key contributor to multi-disciplinary drug development ... and discovery efforts providing an integrated understanding of DMPK properties,...and clinical development of therapeutics across various modalities. The Principal Scientist will guide the design and… more
    Merck (12/12/25)
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  • Principal Scientist

    ADM (Decatur, IL)
    **102923BR** **Job Title:** Principal Scientist - Decatur, IL **Department/Function:** Research & Development **Job Description:** ** Principal Scientist ... in carbohydrate materials and engineering? We are seeking an exceptional Principal Scientist to drive cutting-edge research, development, and engineering… more
    ADM (10/29/25)
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  • Senior Principal Scientist , Peptide…

    Genentech (South San Francisco, CA)
    …We are seeking a highly motivated and experienced Medicinal Chemist (Senior Principal Scientist ) to join our innovative research and development team. ... novel peptide therapeutics into clinical development. You will lead the Medicinal Chemistry efforts for a highly integrated and collaborative team, applying your… more
    Genentech (11/06/25)
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  • Principal Scientist

    J&J Family of Companies (Malvern, PA)
    …Johnson & Johnson Innovative Medicine R&D is recruiting for a Principal Scientist , Biopharmaceutics. This position is a hybrid role ... and will be located in Malvern, PA. We are seeking a highly motivated Principal Scientist to join the Biopharmaceutics team within the Drug Product Development… more
    J&J Family of Companies (12/19/25)
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  • Principal Scientist - TS/MS API…

    Lilly (Indianapolis, IN)
    …essential to our patients around the world. The API EM Senior or Principal Scientist will join the Technical Services/Manufacturing Sciences (TS/MS) team who ... At Lilly, we unite caring with discovery to make life better for people around...and scientific expertise across Peptides and Oligonucleotides (TIDES). The Senior/ Principal Scientist acts as an SME responsible… more
    Lilly (10/07/25)
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  • Principal Scientist , Preclinical…

    Merck (South San Francisco, CA)
    …Pharmaceutical Sciences (DPS) group based in South San Francisco, CA is seeking an Principal Scientist with small molecule and peptide experience. DPS is a ... molecule and biologics developability assessments at the development and drug discovery interface. Our team is responsible for the characterization of pre-clinical… more
    Merck (12/03/25)
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  • Sr. Principal Process Scientist

    Lilly (Lebanon, IN)
    …Eli Lilly and Company is seeking a highly motivated and skilled TSMS Lab Sr. Principal Process Scientist to join our dynamic team. This role focuses on the ... At Lilly, we unite caring with discovery to make life better for people around...synthesis and/or purification, applying a deep understanding of organic chemistry and peptide chemistry principles. + Collaborate… more
    Lilly (11/21/25)
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  • Principal Scientist - Data Foundry…

    Lilly (Indianapolis, IN)
    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. ... to make life better for people around the world. **Lilly Small Molecule Discovery ** is an organization purpose-built to create molecules that make life better for… more
    Lilly (11/11/25)
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  • Principal Scientist , Lab Automation

    J&J Family of Companies (Malvern, PA)
    …at** **https://www.jnj.com/innovative-medicine** **We are searching for the best talent for a Principal Scientist , Lab Automation role to be in Malvern, PA.** ... Laboratory Automation & Robotics team is recruiting for an Integrated Automation Principal Scientist to lead design, development, and implementation of… more
    J&J Family of Companies (11/26/25)
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  • Principal Scientist , Oncology…

    Gilead Sciences, Inc. (Foster City, CA)
    …of our day and improving the lives of patients for generations to come. As a Principal Scientist of Tumor-Intrinsic Biology you will lead a discovery lab and ... Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest… more
    Gilead Sciences, Inc. (12/20/25)
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  • Senior Principal Scientist

    Merck (Rahway, NJ)
    …to join Biologics Process Research & Development (BPR&D) as a Senior Principal Scientist . BPR&D within Research Laboratories is committed to rapidly ... engage with the scientific community to influence the field. As a Senior Principal Scientist , you will drive various strategic initiatives and translate… more
    Merck (12/18/25)
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  • Principal Research Scientist II-…

    AbbVie (Worcester, MA)
    …development and integration of predictive and generative machine learning solutions in drug discovery scientist workflows. This role requires a strong ability to ... and genetic medicines (AAV, LNPs, siRNA etc.) for all therapeutic areas across discovery . Job Description The Principal Data Architect is a visionary leader… more
    AbbVie (11/18/25)
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  • Principal Scientist , Respiratory…

    Merck (South San Francisco, CA)
    **Job Description** We are seeking an experienced scientist to join our team and drive innovation in respiratory medicine. The ideal candidate will bring deep ... setting, with a strong track record of advancing programs from early discovery through clinical development. This role offers the opportunity to shape strategy,… more
    Merck (12/05/25)
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