- Curia (Buffalo, NY)
- SENIOR RESEARCH SCIENTIST , DMPK in Buffalo, NY Curia provides global contract research and manufacturing services to the pharmaceutical and biotechnology ... industries. The Senior Research Scientist , DMPK is an expert in...bioanalytical methods development (and validation), in vitro ADME and PK / PD techniques Knowledge, Skills and Abilities +… more
- Charles River Laboratories (Mattawan, MI)
- …work history and education are added correctly. **Job Summary** We are seeking a ** Research Scientist I** for or our Method Development Bioanalytical Team site ... from non-regulated and regulated studies including preclinical safety evaluations, pharmacokinetic / pharmacodynamic studies, and clinical trials. Staff participate… more
- Merck (South San Francisco, CA)
- …Translational PK / PD organization. The Translational PK / PD Director is an expert mathematical modeler and scientist who can lead development of ... all therapeutic areas for small molecule, peptide, and protein therapeutics. **The Translational PK / PD Director will serve as an individual contributor**… more
- Lilly (Indianapolis, IN)
- …drug with the right dose for the right patient using model-informed drug research and development (MIDD) approaches. To further advance the science in this subject ... area, we are seeking a scientific director who will lead a group of quantitative systems...individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in… more
- Amgen (Washington, DC)
- …also have the opportunity to develop pharmacokinetic ( PK ) and PK pharmacodynamic ( PD ) skills, gain drug-development experience, and represent ... throughout the conduct of clinical pharmacology trials. + Provide interpretation of safety, PK and PD data. + Evaluate prospective clinical trial sites for… more
- Amgen (South San Francisco, CA)
- …ADME/ PK skills such as in vitro ADME, in vivo ADME, biotransformation, PK / PD , or physiologically-based pharmacokinetic modeling (PBPK) to impact project ... will characterize the absorption, distribution, metabolism, excretion (ADME) and pharmacokinetic ( PK ) properties of SM therapeutic drug...+ Expertise with in vitro ADME, in vivo ADME, PK / PD or PBPK + Experience in supporting… more
- Bristol Myers Squibb (Cambridge, MA)
- …molecules towards development candidates and IND. Utilize strong foundational knowledge of building PK PD and efficacy relationship in vivo. + Identify and ... ability to independently develop focused in vivo strategies and utilizing PK / PD /efficacy data to drive discovery, optimization, and characterization of… more
- Bristol Myers Squibb (Cambridge, MA)
- …T cell immunophenotyping, T cell dependent cytotoxicity and cytokine release assays building PK PD and efficacy relationship. + Develop state of the art ... conducting xenograft mouse studies to perform model development, anti-tumor efficacy, PK / PD and combination studies in conjunction with necropsy/tissue/blood… more
- Bristol Myers Squibb (Cambridge, MA)
- …to Proof of Concept in patients. + Characterize therapeutic candidates in vivo and build PK PD and efficacy relationship as part of the lead selection process. + ... required. + Skilled and proficient at independently conducting model development, efficacy, PK / PD and combination studies and perform necropsy and tissue/blood… more
- Bristol Myers Squibb (Seattle, WA)
- …cell-based therapies, immunotherapies, and drug combination studies + Knowledge of pharmacokinetic and pharmacodynamic models to evaluate candidate therapeutics ... In Vivo Pharmacology team in the Cell Therapy Thematic Research Center has an opening for a highly collaborative...an opening for a highly collaborative and creative Principal Scientist with a dedication to discovery and development of… more
- AbbVie (North Chicago, IL)
- …biofluids and tissues. + Perform high-throughput quantitative bioanalysis for In Vitro assays, PK / PD and TK studies of small molecules and peptides in biological ... at AbbVie is seeking a highly motivated and energetic bioanalytical Senior Scientist II to join the High-Throughput Automation Bioassay and Bioanalysis (HT-ABBA)… more
- Bristol Myers Squibb (Summit, NJ)
- …of the disease area(s), KOLs, indication(s), compound(s) under study (including MOA, PK / PD , biomarker & safety profile). + Proficient critical thinking, problem ... lives. Read more: careers.bms.com/working-with-us . The Early Development Clinical Scientist function provides scientific expertise necessary to design and deliver… more
- Daiichi Sankyo Inc. (Basking Ridge, NJ)
- …with Translational Medicine and Clinical Pharmacology to ensure appropriate biomarker, PK / PD measurements; Reviews emerging clinical data regularly; ... focused on providing novel therapies in oncology, as well as other research areas centered around rare diseases and immune disorders. **Summary** Oversees typically… more
- Bristol Myers Squibb (Princeton, NJ)
- …of the disease area(s), KOLs, indication(s), compound(s) under study (including MOA, PK / PD , biomarker & safety profile) + Proficient critical thinking, problem ... Requirements** + 5+ years of experience in clinical science, clinical research , or equivalent + Proficient knowledge of GCP/ICH, drug development process,… more
- ICON Clinical Research (San Antonio, TX)
- …as well as analysis methods, and incorporate the information into PK / PD models. **Supervision:** + The Senior Director of Pharmacometrics R&D supervises ... develops and maintains the NONMEM software designed for statistical analysis in pharmacokinetic and pharmacodynamic data. The development of the software… more
- AbbVie (South San Francisco, CA)
- …methods and techniques in PK / PD field. Act as a lead PK scientist in his/her area of expertise and critically evaluate relevant Clinical Pharmacology, ... projects and Clinical Pharmacology and Pharmacometrics (CPPM) goals. Generate new PK / PD proposals and lead those efforts. Investigate, identify, develop,… more
- Merck (Columbus, OH)
- …has oversight over drug development aspects related to clinical pharmacology, mechanistic PK - PD modeling and pharmacometrics of oncology drugs from post-PCC to ... developing and executing model-based analyses including QSP models and mechanistic PK / PD models into programs thereby strengthening our quantitative capabilities… more
- Regeneron Pharmaceuticals (Tarrytown, NY)
- …Management/Governance meetings with SGD supervision + Collaborate and assist the Pre-clinical PK / PD Team and research teams to characterize preclinical ... We are looking for a highly motivated Principal Scientist , Clinical Pharmacology in our Pharmacometrics (PMx) group.... PK / PD for prediction human PK / PD to accelerate clinical studies and achieve… more
- Regeneron Pharmaceuticals (Tarrytown, NY)
- …day in this role might look like:** Utilizing a mastery level of PK / PD knowledge and strategic leadership skills, effectively develop and implement strategic ... As a Senior Director in Pharmacometrics this individual will be responsible...function and across the organization. * Accountable for the PK / PD evaluation of a portfolio of products… more
- Merck (Columbus, OH)
- …on programs. + Developing and executing model-based analyses including translational PK / PD approaches, population pharmacokinetic models, exposure-response ... **Job Description** We are seeking an experienced talented scientist to join the **Quantitative Pharmacology and Pharmacometrics -** **Immune/Oncology** **(QP2-IO)**… more