- Insmed Incorporated (San Diego, CA)
- …and visualize the effects of therapeutic gene delivery and expression in tissue samples from both preclinical models and clinical studies.The successful candidate ... at the interface of research and development-helping to define tissue -based biomarkers, assess biodistribution, and evaluate treatment-related effects that directly… more
- Insmed Incorporated (San Diego, CA)
- …diseases, including breeding, dosing (ICV, IV), functional assessments, and tissue collection.Perform histological and molecular analyses, including tissue ... biomarker readouts.Support gene therapy translational research by handling human tissue and biospecimens, including processing, storage, and preparation for… more
- Merck & Co. (Rahway, NJ)
- …validation and implementation of LC-MS/MS assays for the analysis of tissue , plasma and other biological samples to support pharmacokinetic, toxicokinetic, clinical ... GLP environment, with duties inclusive of, but not limited to, extracting tissue and plasma samples, setting up instrument analysis, and processing and interpreting… more
- BioAgilytix (San Diego, CA)
- …will have hands-on and leadership experience overseeing regulated bioanalysis, tissue analysis, protein binding, CYP inhibition/induction, CYP phenotyping, and ... HPLC or LC/MS/MS and oversee the following study types: regulated bioanalysis, tissue analysis, protein binding, CYP inhibition, CYP induction, CYP phenotyping or… more
- Legend Biotech USA, Inc. (Raritan, NJ)
- …of cell based products as well as knowledge of Good Tissue Practices.Strong interpersonal and written/oral communication skills.Ability to quickly process complex ... understanding of current Good Manufacturing Practices (cGMP) and current Good Tissue Practices (cGTP) related to CAR-T manufacturing or cell processing.Ability to… more
- Legend Biotech USA, Inc. (Raritan, NJ)
- …of cell based products as well as knowledge of Good Tissue Practices.Strong interpersonal and written/oral communication skills.Ability to quickly process complex ... understanding of current Good Manufacturing Practices (cGMP) and current Good Tissue Practices (cGTP) related to CAR-T manufacturing or cell processing.Ability to… more
- Merck & Co. (Boston, MA)
- …therapeutic programs and grow our scientific capital.Experience:Proficiency of standard tissue culture methods and techniques, including cell line expansion and ... banking.Basic knowledge of lab automation and plate readers with an ability to propose new approaches and experimental designs as needed.A comprehensive understanding of sigmoidal concentration response curves and best practices for curve fitting including… more
- Legend Biotech USA, Inc. (Raritan, NJ)
- …to manufacturing of cell-based products is required.Knowledge of Good Tissue Practices is required.Experience with training methodology, adult learning theory, ... and train-the-trainer programs.Curriculum and module design experience.Detailed knowledge of CAR-T QC test methods and related equipment is requiredExcellent written and oral communication skill are requiredCandidates must be able to accommodate occasional… more
- Merck & Co. (North Wales, PA)
- …ligand 1A (TL1A), which has been shown to be increased in inflamed intestinal tissue and in the systemic circulation of patients with IBD. - Inflammatory bowel ... disease (IBD) is a chronic inflammatory condition affecting the digestive tract and impacting nearly three million people in the US Crohn's disease and ulcerative colitis are two of the most common forms of IBD. The unpredictable symptoms associated with IBD,… more
- Legend Biotech USA, Inc. (Raritan, NJ)
- …of cell based products as well as knowledge of Good Tissue Practices.Experience with training methodology, adult learning theory, instructional design and ... Train-the-Trainer programs.Curriculum and module design experience.Advanced computer skills and practical knowledge of MS Office Suite, SharePoint, and other related systems.Good verbal and written communication skills.Excellent organizational skills.Ability… more
- Legend Biotech USA, Inc. (Raritan, NJ)
- …related to manufacturing of cell-based products is strongly preferred.Knowledge of Good Tissue Practices is required.Knowledge of CAR-T QC test methods and related ... equipment is preferred.Excellent written and oral communication skill are required.Candidates must be able to accommodate shift schedule. Shifts include routine weekend and evening work as required by the manufacturing process.Candidates must be able to… more
- Legend Biotech USA, Inc. (Raritan, NJ)
- …to manufacturing of cell-based products as well as knowledge of Good Tissue Practices.Great attention to detail and ability to follow the procedures.The candidate ... must be highly organized and capable of working in a team environment with a positive attitude under minimal supervision.Good written and verbal communication skills are required.Ability to summarize and present results, and experience with team-based… more
- Daiichi Sankyo, Inc. (Bernards, NJ)
- …to generate a holistic understanding of cellular states, gene regulation, and tissue architecture. We will demonstrate the utility of these models by applying ... them to a complex biomedical challenge, such as identifying novel biomarkers for cancer treatment. The project will address limitations of unimodal approaches, including noise sensitivity and incomplete biological context, by leveraging complementary and… more
- Insmed Incorporated (San Diego, CA)
- …the following is required: general cellular and molecular biology including tissue processing, western blot, cloning, general mammalian cell culture and ... transfection.What You'll Do: Mastery and execution of ddPCR assays developed in partnership with supervisorFollowing protocols and SOPs related to ddPCR lab work with in vitro and in vivo samplesExtraction of DNA , RNA and protein from samples for… more
- Insmed Incorporated (NJ)
- …gene therapy candidates using a broad range of molecular biology and tissue culture techniquesContribute to evaluating AAV gene therapy candidate properties and ... function using in vitro assaysAssist in the development and execution of cell-based biological potency assaysAnalyze and interpret experimental dataMaintain accurate laboratory records and documentationCollaborate with team members on research and development… more
- Insmed Incorporated (NJ)
- …and immunofluorescence, to detect and localize protein targets in tissue sections and cultured cells.Conduct microscopy and analysis in partnership ... with computational scientists, help transition to a high-throughput, AI-driven workflow.Execute multicolor flow cytometry across immune and non-immune cell types, and perform high-purity FACS sorting of rare populations.Support downstream analyses from in vivo… more
- Legend Biotech USA, Inc. (Raritan, NJ)
- …of cell based products as well as knowledge of Good Tissue Practices.Extensive experience participating in regulatory inspections and internal audits.Strong ... interpersonal and written/oral communication skills.Proven people management and leadership experience is required.Experience working with quality systems is required.Extensive knowledge of chemical, biochemical and microbiological concepts is… more
- Legend Biotech USA, Inc. (Raritan, NJ)
- …of cell based products as well as knowledge of Good Tissue PracticesExperience with training methodology, adult learning theory, instructional design and ... Train-the-Trainer programsCurriculum and module design experienceAdvanced computer skills and practical knowledge of MS Office Suite, SharePoint, and other related systemsGood verbal and written communication skillsExcellent organizational skillsAbility to… more
- Legend Biotech USA, Inc. (Raritan, NJ)
- …guidance related to manufacturing of cell-basedproducts is required.Knowledge of Good Tissue Practices is required.Detailed knowledge of CAR-T QC test methods and ... related equipment is preferredExcellent written and oral communication skill are requiredCandidates must be able to accommodate shift schedule. Shifts include routine weekend and evening work as required by the manufacturing process.Candidates must be able to… more
- Legend Biotech USA, Inc. (Raritan, NJ)
- …to manufacturing of cell based products as well as knowledge of Good Tissue Practices.Great attention to detail and ability to follow the procedures.The candidate ... must be highly organized and capable of working in a team environment with a positive attitude under minimal supervision.Good written and verbal communication skills are required.Ability to summarize and present results, and experience with team-based… more
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