- Dana-Farber Cancer Institute (Boston, MA)
- …regulation and cellular signal transduction pathways. + Utilize structural methods such as X - ray crystallography , cryo-EM, or NMR for protein structure ... expertise in protein expression and purification. + Experience with structural methods ( X - ray crystallography , cryo-EM, or NMR) is highly desirable. +… more
- Takeda Pharmaceuticals (Boston, MA)
- …+ Deep and diverse knowledge in multiple areas of structural biology, including X - ray crystallography and cryoEM, using internal and external (CRO) ... Biology and Automation to manage and enhance internal capabilities in crystallography and cryoEM, contribute to computational capabilities and engage with external… more
- Lilly (San Diego, CA)
- …and computational techniques to accelerate generation of high-quality reagents for X - ray crystallography and cryogenic electron microscopy (cryo-EM) ... with protein engineering, protein biochemistry, and protein structure determination by X - ray crystallography or cryo-EM; 2 years of experience with… more
- Lilly (San Francisco, CA)
- …protein characterization, binding analysis and Molecular Dynamics (MD). + Experience in X - ray crystallography and cryo-EM data collection, processing, ... cutting-edge tools, to extract insight from diverse experiments-SPR, NMR, crystallography , cryo-EM, virtual screens-and convert them into actionable hypotheses. Your… more
- Mount Sinai Health System (New York, NY)
- …biology research. Gain hands-on experience with cutting-edge techniques like **cryo-EM** and ** X - ray crystallography ** in a collaborative environment. This ... of the structure and dynamics of disease-related proteins using single-particle cryo-EM, X - ray diffraction, and molecular simulations. You will also participate… more
- AbbVie (North Chicago, IL)
- …methods including AI/ML methodologies into structural biology research. Hands-on experience with X - ray crystallography and cryo-EM data processing and ... about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X , Facebook, Instagram, YouTube, LinkedIn and Tik Tok (https://www.tiktok.com/@abbvie) . Job… more
- J&J Family of Companies (Spring House, PA)
- …of and/or experience with computational chemistry methods and biophysical techniques such as X - ray crystallography and macromolecular NMR is preferred + ... Ability to integrate multiple R&D disciplines into a successful project plan is required + Strong problem-solving skills for developing creative, innovative solutions, and meeting project objectives are required + Demonstrated influence, negotiation, and… more
- Rockefeller University (New York, NY)
- …this process by using a multidisciplinary approach that combines structural biology ( X - ray crystallography and cry-EM) with biochemical,genetic,and cell ... biology techniques. Structural and functional studies of early ribosome assembly intermediates are complemented by the biochemical characterization of multi-protein complexes. Overview The ideal candidate will be working closely with the PI and a small group… more
- Gilead Sciences, Inc. (Foster City, CA)
- …City campus. The Structural Biology Group is well equipped with an advanced X - ray crystallography laboratory and a state-of-the-art cryo-EM facility hosting ... a Glacios and a Krios G4 microscopes. The group provides critical structural information to elucidate the mechanism of action and to facilitate lead molecule optimization, and supports diverse drug discovery projects spanning virology, inflammation, and… more
- Boston College (Chestnut Hill, MA)
- …include a nanofabrication, bioinformatics server, mass spectrometry, flowcytometry, NMR and X - ray crystallography facility. The following are examples ... of typical duties, but other duties may also be assigned. + Development of the research project including planning and designing experiments, data analysis. + Presentation of project results at meetings and seminars. + Publication of high-quality research… more
- Mount Sinai Health System (New York, NY)
- …Responsibilities Docking and structure-based drug design based on known ligands and X - ray crystallography co-crystal data available from collaborator labs. ... Preparation, purification and characterization of compounds in chemistry laboratory; documentation of all experiments in electronic lab notebooks (ELN) including written, publication quality, experimental procedures. Operation and maintenance of laboratory… more
- UTMB Health (Galveston, TX)
- …protein expression and purification, molecular biology, solution biophysics, NMR, X - ray crystallography , cryo-electron microscopy, bioinformatics, and ... computational chemistry (seehttp://www.utmb.edu/core). The University of Texas Medical Branch at Galveston (UTMB) is a major academic health sciences center located on the Texas Gulf Coast. Galveston has a mild, sub-tropical climate with outstanding… more
- Cedars-Sinai (Los Angeles, CA)
- …and aptitudes, other techniques will be applied, such as structure determination by X - ray crystallography and/or more advanced cell-based methodology in use ... in the lab (CRISPR/Cas9, flow cytometry, microscopy, gene knock-out/knock-down, migration assays, etc.). The laboratory has a well-established supervision system for undergrads and master students. The intern will interact daily with the direct supervisor and… more
- Wayne State University (Detroit, MI)
- …production from E. Coli - Protein Crystallization and solution of structure through x - ray crystallography - Computational docking, modeling, and virtual ... screening - Optimize FRET assays to test lead compounds - Determine enzyme kinetic parameters (Km, Ki, kinact determination, etc.) - Protein thermodynamic studies - Optimize lead compounds with medicinal chemists - Public speaking - Mentor/guide graduate… more
- University of Michigan (Ann Arbor, MI)
- …has extensive expertise in developing correlative cryo-ET workflows, and combining X - ray crystallography , single-particle cryo-EM, biochemistry and ... biophysics to dissect protein-nucleic acid systems. **Mission Statement** Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and… more
- UTMB Health (Galveston, TX)
- …mass spectrometry, optical microscopy, flow cytometry, solution biophysics, NMR, X - ray crystallography , cryo-electron microscopy, scientific computing, ... and bioinformatics. Excellent opportunities for scientific interactions exist through sister institutions in the Greater Houston area, Gulf Coast Consortia, and the Keck Center for Interdisciplinary Bioscience. **MINIMUM QUALIFICATIONS:** + Ph.D. **PREFERRED… more
- Dana-Farber Cancer Institute (Boston, MA)
- …are affiliated with state of the art facilities for structural biology (cryo-EM, X - ray crystallography , NMR), chemistry, biophysics, cellular imaging, etc. ... and the lab also has expertise and equipment for mass spectrometry including Bruker timsTOF (HT/Ultra) and Orbitrap Eclipse Tribrid mass spectrometers. Join our highly interactive team of scientists, postdocs, graduate students and technicians to work on… more
- Harvard University (Cambridge, MA)
- …Applicants should possess a Ph.D. and/or MD/Ph.D. degree in structural biology ( X - ray crystallography , NMR or electron microscopy), biochemistry, or ... molecular biology and have a strong publication record Special Instructions For additional information please visit our webpages: http://www.hsph.harvard.edu/farese-walther-lab/ http://cellbio.med.harvard.edu/people/faculty/farese-jr… more
- Kelly Services (Seattle, WA)
- …tools. + Strong proficiency in experimental techniques for protein characterization (eg, X - ray crystallography , NMR, cryo-EM, mass spectrometry). + ... Experience in expression systems such as E. coli, yeast, or mammalian cells. + Excellent analytical, troubleshooting, and problem-solving skills. + Strong communication skills with the ability to effectively present complex information to diverse audiences. +… more
- UTMB Health (Galveston, TX)
- …mass spectrometry, optical microscopy, flow cytometry, solution biophysics, NMR, X - ray crystallography , cryo-electron microscopy, scientific computing, ... bioinformatics and deep computational resources, both locallyand through the University of Texas system. Excellent opportunities for scientific interactions exist through sister institutions in the Texas Medical Center and greater Houston area, Gulf Coast… more