• Merck & Co. (South San Francisco, CA)
    Job DescriptionThe Senior Director (Sr. Principal Scientist ) has primary responsibility for the strategic planning and directing clinical research activities ... investigational compounds in Immunology. With a focus on late-stage development, the Senior Clinical Director will manage the entire cycle of clinical development,… more
    HireLifeScience (10/25/25)
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  • Senior / Principal Scientist

    Genentech (South San Francisco, CA)
    …Ph.D. level Senior Scientist , Principal Scientist , or Senior Principal Scientist who is driven to use cutting edge modeling approaches ... (for Principal Scientist ), or 7+ years (for Senior Principal Scientist ) of industry, regulatory, and/or related post-doctoral experience Relocation… more
    Genentech (09/30/25)
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  • Principal / Senior Principal

    Genentech (South San Francisco, CA)
    …location of California is $141,500-$262,900 ( Principal Scientist ) and $176,600-$328,000 ( Senior Principal Scientist ) . Actual pay will be determined ... and biomarker approaches.** **We are seeking a highly motivated Principal or Senior Principal Lab...Neuroimmunology or a related field, with minimum 2 years ( Principal Scientist ) 5 years (Sr. Principal more
    Genentech (10/15/25)
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  • Senior / Principal Scientist

    Genentech (South San Francisco, CA)
    …discovery in target identification, disease understanding, and therapeutic exploration. As a Senior / Principal Scientist , you will lead scientific initiatives ... based on the primary location of California, is ( Senior Scientist : $167,400 - 310,800) and ( Principal Scientist : $194,000 - 360,400). Actual pay will be… more
    Genentech (10/02/25)
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  • Senior Principal Scientist

    Merck (South San Francisco, CA)
    **Job Description** The Senior Director (Sr. Principal Scientist ) has primary responsibility for the strategic planning and directing clinical research ... investigational compounds in Immunology. With a focus on late-stage development, the Senior Clinical Director will manage the entire cycle of clinical development,… more
    Merck (10/25/25)
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  • Technical Development Senior

    Genentech (South San Francisco, CA)
    …(molecular assessment) through post product launch. **The Opportunity** A Technical Development Senior Principal Scientist position is available in ... Genentech's Analytical Development and Quality Control (ADQC) department for US Biologics in the Pharma Technical Development (PTD) organization. The individual will lead a multidisciplinary team of analytical, biological, and quality control scientists in… more
    Genentech (09/17/25)
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  • Lab Head, Senior Principal

    Genentech (South San Francisco, CA)
    …Department of Discovery Oncology at Genentech is seeking a highly motivated and accomplished Senior Principal Scientist , Lab Head with a strong background in ... oncology drug discovery. The ideal candidate will bring deep scientific expertise in targeting oncogenic signaling pathways, particularly KRAS, the MAPK pathway, or other key cancer-driving mechanisms, and will have a track record of impactful research in drug… more
    Genentech (09/06/25)
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  • Principal Applied Scientist

    Amazon (Palo Alto, CA)
    …a clear customer value proposition. Advancing Scientific and Technical Capabilities: As a senior leader, the Principal Scientist will play a critical ... responsibilities include but are not limited to: Improving Auction Mechanism: The Principal Scientist will reimagine auction mechanisms to holistically optimize… more
    Amazon (10/25/25)
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  • Principal Applied Scientist

    Amazon (Mountain View, CA)
    …fine-tuning, and Applied Machine Learning within professional service contexts. As a principal scientist , you will be the bridge between scientific advancement, ... Description As a Principal Applied Scientist on our Agentic...driving innovation, and representing the company's AI capabilities to senior leadership at customer organizations while ensuring our solutions… more
    Amazon (10/28/25)
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  • Principal Applied Scientist

    Amazon (Palo Alto, CA)
    Description The Sponsored Products (SP) team is looking for a Principal Scientist to help our millions of shoppers intuitively navigate our vast inventory by ... and break fresh ground in product and technical innovations every day! As a Principal Scientist in Sponsored Products, you will have deep subject matter… more
    Amazon (10/07/25)
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  • Principal Applied Scientist , AGI…

    Amazon (Sunnyvale, CA)
    Description As a Principal Scientist within the Artificial General Intelligence (AGI) organization, you are a trusted part of the technical leadership. You bring ... automated curricula, and science of scaling. Lead cross‑org initiatives. Mentor senior scientists and engineers. Own delivery under strict timelines. Ship production… more
    Amazon (07/31/25)
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  • Principal Scientist II, Molecular…

    Roche (Santa Clara, CA)
    …technologies to significantly enhance DNA sequencing workflows. We are seeking a Principal Scientist II, Molecular Biology and Microfluidic Systems Integration, ... **This is a critical, hands-on leadership role for a scientist who is passionate about pioneering new technologies and...findings and progress to the team, the organization and senior leadership. + You will identify and champion new… more
    Roche (09/19/25)
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  • Sr Principal Applied Scientist

    Amazon (Santa Clara, CA)
    Description As a Senior Principal Scientist in AGI, you will have deep subject matter expertise in the area of large language models and generative AI across ... conferences or journals. Strong prior experience with mentorship and/or management of senior scientists and engineers. Thinks strategically, but stays on top of… more
    Amazon (10/07/25)
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  • Principal Data Scientist

    Genentech (South San Francisco, CA)
    …a thriving culture built on collaboration and innovation. **Job Summary** The ** Principal Data Scientist ** develops and maintains AI-enabled data science ... market, customer, and competitive insights into forward‑looking AI strategies with senior stakeholders, ensuring solutions not only enhance the integrated customer… more
    Genentech (10/23/25)
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  • Principal Data Scientist

    Microsoft Corporation (Mountain View, CA)
    …accelerate future challenges and contribute to the Microsoft platform. We are hiring a ** Senior and** ** Principal Data Scientist ** **s** to help drive ... high-impact engineering projects with our customers and their partners, transforming their missions using AI and other cloud-based solutions and services. Data scientists have data management and expertise in developing statistical techniques to analyze data… more
    Microsoft Corporation (10/22/25)
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  • Principal Data Scientist

    Intuit (Mountain View, CA)
    **Overview** We are seeking an experienced and highly motivated Principal Data Scientist to join our Platform Data Science and Analytics team at Intuit. This ... skills with the ability to influence and collaborate effectively with senior leadership and cross-functional partners. + Track record of embedding analytics… more
    Intuit (10/21/25)
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  • Principal Data Scientist

    Microsoft Corporation (Mountain View, CA)
    …science problems across users, advertisers, and publishers. We are looking for a ** Principal Data Scientist ** leader, creative modeling geeks who are willing to ... evaluation. + Excellent communication to be able to communicate insights to senior leaders. + Experience with driving large collaboration across multiple teams. +… more
    Microsoft Corporation (10/16/25)
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  • Principal Scientist , Oncology…

    Gilead Sciences, Inc. (Foster City, CA)
    …together. **Position Overview:** We are seeking a highly motivated and creative Principal Scientist to support Gilead's growing Oncology targeted large molecule ... portfolio. The successful candidate will be an integral senior member of a high performing research team dedicated to (i) identifying and validating novel targets… more
    Gilead Sciences, Inc. (09/11/25)
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  • Principal Scientist in Biologics…

    Gilead Sciences, Inc. (Foster City, CA)
    …Description** **Job Description:** We are seeking a talented and highly motivated Principal Scientist for our Pivotal and Commercial Biologics Characterization ... Chemistry to products and problems. + Works in collaboration with more senior scientists or scientific directors to advance the development of state-of-the-art… more
    Gilead Sciences, Inc. (09/11/25)
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  • Principal Controls Scientist

    Amazon (Sunnyvale, CA)
    …Echo, and the Astro household robot. What will you help us create? As a Principal Controls Scientist , you will be responsible for developing solutions to control ... engineering requirements and identify trade-offs and sensitivities - Mentor junior and senior engineers in good design practice; actively participate in hiring of… more
    Amazon (10/22/25)
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