• Merck & Co. (South San Francisco, CA)
    Job DescriptionWe are seeking an exceptional computational protein engineer to join the Discovery Biologics Protein Engineering department in South San Francisco to ... in support of our biotherapeutic portfolio drug discovery programs. The Principal Scientist, Computational Protein Engineering role will be a key contributor… more
    HireLifeScience (08/22/25)
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  • DataRobot (San Francisco, CA)
    …AI that makes sense for their business - today and in the future. As a Principal Software Engineer for Generative AI at DataRobot, you will be the technical ... teams, influencing roadmap priorities. + Mentor Staff/Senior Engineers, elevating the team's technical bar through design reviews, best practices, and knowledge… more
    DirectEmployers Association (10/09/25)
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  • Stanford Health Care (Newark, CA)
    …of America) **This is a Stanford Health Care job.** **A Brief Overview** As a Principal System Engineer - Cloud Services, You will oversee Stanford Health Care's ... Health Care **What you will do** + Cloud Infrastructure Management: Design , implement, and manage scalable cloud infrastructure (Azure/AWS/GCP) to support modern… more
    DirectEmployers Association (08/12/25)
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  • Principal Design Technical

    Microsoft Corporation (Mountain View, CA)
    …Azure cloud servers, clients, and augmented reality. We are looking for a ** ** ** Principal ** ** Design ** ** Technical Engineer ** to work in the dynamic ... must be a highly motivated self-starter who will thrive in this cutting-edge technical environment. You will be responsible for developing and maintaining the RTL … more
    Microsoft Corporation (10/14/25)
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  • Principal Engineer , Front-End…

    Microsoft Corporation (Mountain View, CA)
    …Level) handoff, and IP(Intellectual Property) integration. **We are looking for a Principal Engineer , Front-End Computer-Aided Design Software to join ... Silicon Engineering and Solutions Team is seeking a **software engineer ** to serve as a technical leader...can thrive at work and beyond **Responsibilities** In the ** Principal Engineer , Front-End Computer-Aided Design more
    Microsoft Corporation (10/11/25)
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  • Principal Logic Design

    Microsoft Corporation (Mountain View, CA)
    …that will manage and optimize the Cloud infrastructure. We are looking for a ** Principal Logic Design Engineer ** to join the team. \#SCHIE ... for test (DFT), and other teams to optimize tradeoffs within the design . + Provide technical leadership through mentorship and teamwork **Qualifications**… more
    Microsoft Corporation (10/11/25)
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  • Senior Principal Mechanical Engineer

    Roche (South San Francisco, CA)
    …the Director of Design Engineering, the Design Engineering Senior Principal Mechanical Engineer provides technical leadership and accountability for ... on project designs. **Project Technical Analysis & Design Guidance, continued:** + The Senior Principal ...& Design Guidance, continued:** + The Senior Principal Mechanical Engineer will also provide management… more
    Roche (10/14/25)
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  • Principal Silicon Design

    Microsoft Corporation (Mountain View, CA)
    …will manage and optimize the Cloud infrastructure. We are looking for a ** Principal Design Verification** ** Engineer ** to join the team. **Responsibilities** ... based functions and features. + Interact with architects and design engineers to create testplans covering verification strategy, test requirements,… more
    Microsoft Corporation (10/10/25)
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  • Principal /Senior Principal Software…

    Genentech (South San Francisco, CA)
    …Software Engineer ); 12+ years of experience (Sr. Principal Software Engineer ) + Deep experience and technical understanding of modern web application ... this position based on the primary location of California is $162,600 - $302,000 ( Principal Software Engineer ) and $189,200 - $351,400 (Senior Principal more
    Genentech (09/06/25)
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  • Principal Information Systems…

    City and County of San Francisco (San Francisco, CA)
    …minimum qualifications. Application Deadline: Continuous How to Apply: Applications for Principal Information Systems Engineer - Applications Specialty are only ... systems together as an enterprise networking backbone. The 1044 Principal Applications Engineer is the highest level...expert, performs work requiring a very high level of technical knowledge of a specific area or ability to… more
    City and County of San Francisco (08/08/25)
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  • Principal Information Systems…

    City and County of San Francisco (San Francisco, CA)
    …the minimum qualifications. Application Deadline: Continuous How to Apply: Applications for Principal Information Systems Engineer - Networks Specialty are only ... systems together as an enterprise networking backbone. The 1044 Principal Networks Engineer is the highest level...expert, performs work requiring a very high level of technical knowledge of a specific area or ability to… more
    City and County of San Francisco (08/08/25)
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  • Principal Staff Software Engineer

    LinkedIn (Mountain View, CA)
    …that power the visibility, cost attribution and planning of LinkedIn Infrastructure. As a Principal Engineer , they will mentor team members, uphold a high bar ... take an engineering-first approach to elevate infrastructure. As a Principal Engineer , you'll be driving the strategy...practical experience + 10+ years of experience in software design /development + 7+ years in a technical more
    LinkedIn (09/30/25)
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  • Principal Engineer , VCF Cluster…

    Broadcom (Palo Alto, CA)
    technical excellence. **Job Summary** We are seeking a highly experienced and visionary Principal Engineer to join our VCF Cluster Management team. In this ... 50 years of innovation, collaboration, and engineering excellence. We design , develop, and supply a broad range of semiconductor...at least 5 years in a lead architect or principal engineer role focusing on distributed systems.… more
    Broadcom (07/29/25)
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  • Principal , UX Designer / Engineer

    Walmart (San Bruno, CA)
    **Position Summary ** **What you'll do ** ** Principal UX Designer / Engineer , AI Systems - Design Organization** **What you'll do** As a Principal UX ... Designer / Engineer , AI Systems in the Design Organization, you will: + **Implement and Productionize AI...strategies, incident response, and continuous improvement. + **Architect AI-Powered Design Tools:** Lead the technical design more
    Walmart (09/23/25)
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  • Principal Software Engineer - Data…

    Intuit (Mountain View, CA)
    **Overview** Come join the Virtual Expert Platform Data Engineering Team as a Principal Software Engineer . Intuit is the global leader in financial management ... disrupting ourselves as we identify major new technology and design trends that are needed to deliver our mission...to meet their unique requirements and scale. As a Principal Software Engineer , you will define and… more
    Intuit (10/02/25)
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  • R & D Software Engineer - Principal

    Broadcom (Palo Alto, CA)
    …A Visionary Technical Leader** We are seeking a highly experienced and visionary Principal Engineer to join our VCF vCenter team. In this pivotal role, you ... will be responsible for defining the technical vision, architecting, and leading the implementation of complex...at least 5 years in a lead architect or principal engineer role focusing on distributed systems… more
    Broadcom (09/18/25)
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  • Principal Cybersecurity Engineer

    City and County of San Francisco (San Francisco, CA)
    …Under the direction of the Director, Cybersecurity and Compliance, the Principal Cybersecurity Engineer analyzes, plans, designs, implements, maintains, ... and ongoing support of preventative detective and corrective controls. The Principal Cybersecurity Engineer identifies, refines, and analyzes cybersecurity data… more
    City and County of San Francisco (10/09/25)
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  • Principal Software Engineer

    Microsoft Corporation (Mountain View, CA)
    …major Microsoft products, including Office, Windows, Bing, SQL Server, and Dynamics. As a Principal Engineer on the team, you will have the opportunity to work ... achieving Microsoft Azure's capex goals. This is a hands-on technical role requiring software design and development...locations considered for very strong candidates. **Responsibilities** As a Principal Engineer on the team the common… more
    Microsoft Corporation (10/14/25)
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  • Principal Software Engineer

    General Motors (Mountain View, CA)
    …Center three times per week._ **The Role** General Motors is seeking a ** Principal Software Engineer ** to provide technical leadership and architectural ... role will be responsible for defining, influencing, and driving the long-term technical vision of our platform to ensure _scalability_ , performance, and innovation.… more
    General Motors (09/25/25)
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  • Principal /Senior Principal Machine…

    Genentech (South San Francisco, CA)
    …field and 6+ years of professional experience in machine learning engineering roles ( Principal Machine Learning Engineer ); 12+ years (Senior Principal ... evolving to meet the scientific needs. **The Opportunity:** As a machine learning engineer in AI Enablement, you will be working closely with folks that span… more
    Genentech (09/06/25)
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