- Merck & Co. (South San Francisco, CA)
- …optimization in support of our biotherapeutic portfolio drug discovery programs. The Principal Scientist , Computational Protein Engineering role will be a key ... to guide antibody and protein design and optimizationApply cutting-edge AI /machine learning models to support drug discovery and engineering projectsIntegrate… more
- Intuit (Mountain View, CA)
- **Overview** Come join our collaborative and creative group of AI scientists and machine learning engineers and build models that directly affect hundreds of ... techniques + 3+ years as either a lead in a AI science role or in a management position in AI science + Strong communication skills and proven experience as an… more
- Microsoft Corporation (Mountain View, CA)
- …and intelligence services to transform how Microsoft collects, generates, manages, and shares AI training data. We are seeking Principal Applied Scientists to ... Join Microsoft's CoreAI team to build the AI Data Platform, the foundation for secure, scalable,...secure, scalable, reusable datasets that power model development. The AI Data Platform team's mission is to build a… more
- Genentech (South San Francisco, CA)
- …in target identification, disease understanding, and therapeutic exploration. As a Senior/ Principal Scientist , you will lead scientific initiatives that bridge ... expert and innovator, capable of shaping scientific direction and organizational strategy. Principal Scientist + PhD (or equivalent) in a quantitative discipline… more
- Amazon (Sunnyvale, CA)
- Description As a Principal Applied Scientist within the Artificial General Intelligence (AGI) organization, you are a trusted part of the technical leadership. ... affect the way we build and integrate algorithms. A Principal Applied Scientist will solicit differing views...a critical role in driving the development of Generative AI (GenAI) technologies that can handle Amazon-scale use cases… more
- Amazon (Sunnyvale, CA)
- …General Intelligence (AGI) Team is seeking a highly skilled and experienced Principal Applied Scientist to support adoption and enable customization of ... and knowledge distillation across large language models. As a Principal Applied Scientist , you will play a...cases - Contribute to the development of the Responsible AI toolkit, including creating training and evaluation datasets for… more
- Amazon (Palo Alto, CA)
- …possible with AI , join us in shaping the future of advertising. The principal scientist in this position will focus on designing, developing and launching ... the boundary of what's possible in these fields. Key job responsibilities As a Principal Applied Scientist for the team, you will drive appropriate technology… more
- Amazon (Palo Alto, CA)
- Description The Sponsored Products (SP) team is looking for a Principal Scientist to help our millions of shoppers intuitively navigate our vast inventory by ... in product and technical innovations every day! As a Principal Scientist in Sponsored Products, you will...abreast of the latest developments in the space of AI /ML/GenAI modeling and identify opportunities to improve the efficiency… more
- Microsoft Corporation (Mountain View, CA)
- We're hiring a ** Principal Applied Scientist ** with expertise in areas such as Deep Learning, Ad Tech, Ads Recommendation Systems, Sequential Modeling and Large ... (LLMs). Join the Signals Modeling team, part of Microsoft AI Ads Engineering, to shape the future of advanced...week from the designated location. In this role, the Principal Applied Scientist will design and implement… more
- Amgen (South San Francisco, CA)
- …Join us and transform the lives of patients while transforming your career. ** Principal Scientist - Clinical Pharmacology, Modeling & Simulation** **What you ... Modeling & Simulation Department at Amgen is seeking a Principal Scientist . In this vital role, you...modeling - integrated with emerging Machine Learning and Generative AI approaches - to innovatively guide optimal clinical drug… more
- Microsoft Corporation (Mountain View, CA)
- …visualizations to cloud engineering and management partners. We are looking for a Data Scientist and AI expert to support our custom data analytics and ... visualizations platform as well and building and implementing AI solutions across our division. This high-impact role combines...improve efficiency, quality and innovation and our looking for ** Principal Data Scientist ** to join our team!… more
- Walmart (Sunnyvale, CA)
- …include ability to build, deploy, maintain and troubleshoot large scale systems. As a Principal (ML Engineer) Data Scientist , you'll have the opportunity to + ... is focused on using the latest research in generative AI (GenAI), artificial intelligence ( AI ), machine learning...personalization. **What you'll do:** We are looking for a Principal Machine Learning Engineer who can help build large… more
- Amazon (Sunnyvale, CA)
- …General Intelligence (AGI) team is looking for a passionate, talented, and inventive Principal Applied Scientist with a strong deep learning background, to lead ... the development of industry-leading technology with multimodal systems. As a Principal Applied Scientist , you are a trusted part of the technical leadership. You… more
- Microsoft Corporation (Mountain View, CA)
- The Advanced Reasoning Group is hiring a ** Principal Applied Scientist ** at **Mountain View, CA** , or **Redmond, WA.** The team is responsible for creating and ... partnerships across the org. We are looking for a Principal Applied Scientist to deliver a state-of-the-art...agent, and related ecosystems. Starting January 26, 2026, Microsoft AI (MAI) employees who live within a 50-mile commute… more
- Amazon (Santa Clara, CA)
- Description Amazon Web Services (AWS) is looking for a Principal Applied Scientist to join the Amazon Q team. Q is AWS's enterprise generative AI assistant ... team, you will lead research and development efforts in generative AI and Agentic AI to enable intelligent agents that perform complex reasoning, automate… more
- Microsoft Corporation (Mountain View, CA)
- …Management Platform (DMP), part of Microsoft AI (MAI) is hiring for a ** Principal Applied Scientist ** in **Redmond, WA** or **Mountain view, CA** . The Data ... data while preserving user trust and privacy. As a ** Principal Applied Scientist ** in User Mapping Service,...user graphs for various policies for all across Microsoft AI organization, track metrics, generate user identity cluster score,… more
- Amazon (Sunnyvale, CA)
- …Prime Video's technology teams are redefining the digital video experience at scale. As a Principal Applied Scientist at Prime Video, you will be a technical and ... strategic leader responsible for inventing, developing, and deploying groundbreaking AI solutions that power personalized, relevant, and delightful experiences for… more
- Amazon (Santa Clara, CA)
- Description We are seeking a Principal Applied Scientist to lead Amazon Customer Service's (ACS) text-based AI initiatives. In this role, you will spearhead ... the development of our large language model foundations and agentic AI solutions for customer service automation. You will architect scalable chatbot solutions that… more
- Intuit (Mountain View, CA)
- **Overview** We are seeking an experienced and highly motivated Principal Data Scientist to join our Platform Data Science and Analytics team at Intuit. This ... measurement, as well as experience in developing evaluation frameworks for Generative AI (GenAI) and agentic workflows such as GenAI-powered digital assistants. This… more
- Amazon (Sunnyvale, CA)
- …Amazon products every day. Come join our team! Key job responsibilities As a Principal Applied Scientist , you will: * Own the technical architecture and ... on-device ML models for Amazon's hardware products, including audio, vision, and multi-modal AI features. We work at the critical intersection of ML innovation and… more
