- BioSpace (Boston, MA)
- …includes active investments in Oligonucleotide development, nanomedicines for tissue specific targeting and other gene delivery strategies. The drug product ... team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, Antibody Drug Conjugates and AAV and other non-viral vector delivery. We are seeking highly motivated professionals with an experience in developing… more
- Texas A&M University System (College Station, TX)
- …. Specifically, the project will investigate the potential of targeting a haplolethal gene for effective genetic control ... to analyze the intricate dynamics of a homing rescue drive targeting haplolethal gene in Aedes aegypti mosquito populations. Additionally, it will evaluate the… more
- University of Miami (Miami, FL)
- …electroporation and pronuclear or cytoplasmic injection of DNA and CRISPR gRNA/cas9; and gene targeting by electroporation and injection of ES/iPS cells into ... new services for the generation of transgenic, knock-out, knock-in and gene -edited mice, as well as developing and adapting state-of-the-art editing technologies… more
- University of Utah (Salt Lake City, UT)
- …The Mutation Generation and Detection ( MGD ) Core Facility and the Transgenic & Gene Targeting Mouse ( TGTM ) Core Facility work together to provide state ... of the art service and assistance in the field of mouse transgenics and gene targeting . The MGD core has the resources to carry out all the molecular techniques… more
- University of Miami (Miami, FL)
- …genetic engineering services. These services include the use of CRISPR/Cas9 targeting to produce gene knockouts, conditional knockouts, single-point mutations, ... and insertions and gene fusions, also simultaneously mutating multiple genes in a...mice, knock-in (KI) mice generation using traditional ES cell targeting including C57BL6 ESCs; ES cell, tetraploid and iPS… more
- Lilly (Boston, MA)
- …includes active investments in oligonucleotide development, nanomedicines for tissue specific targeting and other gene delivery strategies. The drug product ... team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, antibody drug conjugates, AAV, and other non-viral vector delivery. We are seeking a highly motivated scientist with an interest in leading modeling… more
- University of Florida (Palm Beach, FL)
- …mining, and development of enabling technologies for natural product (NP) biosynthetic gene cluster (BGC) activation in native producers or heterologous hosts, (ii) ... microbial taxa and ecological niches, and revealing the vast diversity of NP biosynthetic gene clusters (BGCs) that far exceeds the number of microbial NPs known to… more
- University of Pennsylvania (Philadelphia, PA)
- …responsibilities may include research to complement and expand the world-leading retinal gene therapy program already well established at the Center for Hereditary ... regenerative medicine, genome engineering, neuroscience, or artificial intelligence directly targeting human conditions. This position is not intended for physicians… more
- Catalent Pharma Solutions (Harmans, MD)
- **Manager, Commercial Operations** Catalent Cell and Gene Therapy is looking to recruit **a Manager of Commercial Operations** to join our growing team in Maryland. ... and oncolytic viruses. Our FDA-licensed, state-of-the-art CGMP manufacturing facility for Gene Therapies is located on the Harmans/BWI campus. The campus, featuring… more
- University of North Carolina- Chapel Hill (Chapel Hill, NC)
- …to begin as early as May 1 2025. The Spanheimer lab studies how gene regulation impacts response to treatment in breast cancer. Particular areas of emphasis are ... from tumors and how we can prevent resistance by targeting unique vulnerabilities of those cells. The purpose of...testing in vitro models including CRISPR -CAS9 knockouts and gene regulation assays including mRNA sequencing and CUT and… more
- Johns Hopkins University (Baltimore, MD)
- …neurological diseases lack disease-modifying treatments, but novel DNA and RNA- targeting drugs have recently been approved for muscular dystrophies, spinal ... private sectors. **Minimum Qualifications** + Master's Degree in genetics, cell and gene therapy, biomedicine or directly related discipline. + Seven years of… more
- Mount Sinai Health System (New York, NY)
- …of first-in-class small molecule inhibitor/chemical probes as well as proteolysis targeting chimera (PROTAC) degraders for targeted protein degradation (TPD) and ... DNA, RNA, Protein isolation; conventional PCR and gel electrophoresis; RTqPCR; gene cloning experiments; virus preparation and cell transfection and infection;… more
- Bill and Melinda Gates Foundation (Seattle, WA)
- …and invest in the innovation to improve the performance, coverage, and targeting of interventions for all three, including 'moonshots' like genetically modified ... vaccines. A fundamental enabler of interventions is accurate, timely, and geo-localized targeting . To improve this, we advocate for and support countries in their… more
- Bill and Melinda Gates Foundation (Seattle, WA)
- …and invest in the innovation to improve the performance, coverage, and targeting of interventions for all three, including 'moonshots' like genetically modified ... fundamental enabler of interventions is accurate, timely, and geo-localized targeting . To improve this, we advocate for and support...(eg, bed nets), and genetically modified mosquitoes ( eg, gene drive mosquitoes ). In this role, y ou… more
- Astellas Pharma (South San Francisco, CA)
- …+ Seek and apply innovative approaches to understand tumor resistance to therapies targeting oncogene addiction and beyond + Act as an oncology expert in cross ... the disease. + Experience with advanced molecular biology techniques including CRISPR/Cas9 gene editing, flow cytometry, and cell culture of both, primary tumor… more
- Danaher Corporation (Marlborough, MA)
- …biological research to developing innovative vaccines, new medicines, and cell and gene therapies. At Cytiva you will be able to continuously improve yourself ... and qualification efforts, including re-engaging lost/stalled opportunities and preshow targeting initiatives. + Provide actionable feedback to management to support… more
- Penn State Health (Hershey, PA)
- …the development and clinical translation of novel vaccine and cellular immunotherapies targeting pediatric solid tumors. The director will also spearhead gene ... therapy initiatives for non-malignant hematologic conditions, particularly sickle cell disease, ensuring integration of translational research with compassionate, high-quality clinical care. The successful candidate will foster collaborations across basic… more
- AbbVie (Cambridge, MA)
- …While existing technologies, such as bifunctional degraders, have transformed the targeting of intracellular proteins, the degradation of cell surface proteins ... research. + Experience with advanced molecular biology techniques including CRISPR/Cas9 gene editing, flow cytometry, and confocal microscopy. + Strong track record… more
- Dana-Farber Cancer Institute (Boston, MA)
- The Cancelas Lab seeks a Postdoctoral Scientist to study leukemogenesis and targeting in leukemia. The applicant should have a doctoral degree in Biology, Molecular ... all - of the following techniques: PCR, molecular cloning, viral transduction, gene editing, immunoblotting, cell culture, colony-formation assays, ex vivo and in… more
- University of Rochester (Rochester, NY)
- …and are at the cutting edge of promising new gene therapies. The Division of Multiple Sclerosis and Neuroimmunology ... therapeutics of MS. The Division oversees research assessing novel immunotherapies targeting multiple steps in the pathogenesis of MS, evaluating new symptomatic… more
