- Merck & Co. (South San Francisco, CA)
- …and optimization in support of our biotherapeutic portfolio drug discovery programs. The Principal Scientist , Computational Protein Engineering role will be ... protein structure prediction and modeling techniques to guide antibody and protein design and optimizationApply cutting-edge AI/machine learning models to… more
- Merck & Co. (Rahway, NJ)
- Job Description BPR&D Downstream Principal Scientist Job Description: - - Our Scientists are our Inventors. Using innovative thinking, state-of-the-art ... downstream bioprocessing to join Biologics Process Research & Development (BPR&D) as a Principal Scientist .- - BPR&D within our company's Research Lab oratories… more
- Merck & Co. (Rahway, NJ)
- …the life of the project, tries to resolve problems during the design and planning phases whenever possible.Provides timely and accurate information and status ... down establishment, computational fluid dynamics (CFD) modeling, Quality by Design (QbD) and Lean Six Sigma principles. Experience supporting/writing regulatory… more
- BioAgilytix (Durham, NC)
- … Scientist III to serve as Bioanalytical Project Manager (BPM)/ Principal Investigator (PI), overseeing all aspects of bioanalytical studies-including project ... the future of healthcare.Essential Responsibilities:Serve as Bioanalytical Project Manager (BPM)/ Principal Investigator (PI), overseeing all aspects of bioanalytical studies… more
- BioAgilytix (San Diego, CA)
- …and leadership experience overseeing regulated bioanalysis, tissue analysis, protein binding, CYP inhibition/induction, CYP phenotyping, and metabolite profiling/ID. ... for team performance and outcomes.Leading teams through transitions and new initiatives. Design and execute experiments efficiently and assign tasks appropriately to… more
- Howard Hughes Medical Institute (HHMI) (Chicago, IL)
- …pathways and identify druggable targets Apply structure-based engineering to design and develop protein -based therapeutics Collaborate across multidisciplinary ... protein biochemistry experiments Conduct structural biology studies and analyze protein structures Design and execute cell-based assays for functional… more
- Regeneron Pharmaceuticals (Tarrytown, NY)
- We are seeking a highly skilled and motivated Principal Scientist with expertise in computational biology, protein structural modeling and engineering, and ... the intersection of biology, computation, and automation. **As a Principal Scientist in the Bispecifics Group, a...engineering is a plus. Familiarity with AI-assisted de novo protein design is required. Experience with high-throughput… more
- Merck (South San Francisco, CA)
- …and optimization in support of our biotherapeutic portfolio drug discovery programs. The Principal Scientist , Computational Protein Engineering role will be ... protein structure prediction and modeling techniques to guide antibody and protein design and optimization + Apply cutting-edge AI/machine learning models to… more
- Bristol Myers Squibb (Brisbane, CA)
- …Summary** We are seeking an enthusiastic, creative, and versatile Principal Scientist to join our collaborative Protein Engineering team in Redwood ... new ideas in the laboratory and thrives on the design -build-test cycle. You will solve complex protein ...the design -build-test cycle. You will solve complex protein engineering problems and implement robust platforms for … more
- Regeneron Pharmaceuticals (Tarrytown, NY)
- …from our state-of-art research facilities. A typical day in the life of a Senior Principal Scientist AI/ML Antibody Design and Engineering may include the ... We are seeking a highly talented and motivated Senior Principal Scientist specializing in AI Machine Learning...with expertise in programming, large language models, in silico protein design tools, and knowledge in structural… more
- Bristol Myers Squibb (Cambridge, MA)
- …DESCRIPTION** We are seeking an experienced and collaborative ** Principal AI Scientist ** to lead the design and deployment of **multi- objective optimization ... and predictive modeling solutions** for biologics discovery and design . This role is an integral part of our **Computational Design and Predictive Modeling… more
- ConvaTec (Lexington, MA)
- …work and stakeholder management are critical to success within this role. The principal scientist will apply subject matter expertise in cell culture, tissue ... pivot as new information becomes available. In addition, the principal scientist will be key contributor to...research programs related to biointerfaces and tissue engineering. + Design and conduct the hands-on research for projects in… more
- AbbVie (North Chicago, IL)
- …typically 10 years of experience, PhD and typically 4 years of experience. + Principal Research Scientist I: BS or equivalent education and extensive, Typically, ... and effectiveness of key results of major project plans through sound design , early risk assessments, and implementation of fallback strategies. + Sources and… more
- AbbVie (Worcester, MA)
- …protein , biologics, fragments, or multispecifics (eg bispecifics, trispecifics, bispecific protein fusions) design , expression and purification + Experience ... Engineering group at AbbVie is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting Discovery Biotherapeutics and lead a… more
- Boehringer Ingelheim (Ridgefield, CT)
- …NBE (New Biological Entity) - Pharmacokinetics group, the successful Principal /Senior Principal Scientist will design and implement mechanistic PK/PD and ... of Boehringer Ingelheim's highly innovative pre-clinical NBE portfolio. This scientist will represent the PK/PD modeling discipline on multi-disciplinary drug… more
- Amgen (Cambridge, MA)
- …Amgen team. Join us and transform the lives of patients while transforming your career. Principal Scientist **What you will do** Let's do this. Let's change the ... serving as analytical subject matter expert to support and advise design of characterization studies, data analysis and investigations. + Provide analytical… more
- Merck (Rahway, NJ)
- …bioprocessing to join Biologics Process Research & Development (BPR&D) as a Principal Scientist . BPR&D within our company's Research Laboratories is on ... publish and engage with the scientific community to influence the field. As a Principal Scientist you will have the opportunity to influence the future direction… more
- Bristol Myers Squibb (Cambridge, MA)
- …lives. Read more: careers.bms.com/working-with-us . Job Requisition: Senior Principal Scientist , Development DMPK Challenging. Meaningful. Life-changing. ... across the globe. PCO is looking for a Senior Principal Scientist to join the Dev DMPK...and pharmaceutical drug development of small molecule drugs and protein therapeutics. In this role, you will represent the… more
- AbbVie (Cambridge, MA)
- …applying advanced computational modeling and AI/ML approaches to optimize therapeutic protein design , enhance production efficiency, and accelerate genetic ... novel technology innovation across AbbVie's therapeutic and functional areas. . Design and implement advanced AI/ML algorithms tailored to tackling complex problems… more
- Merck (West Point, PA)
- …studies to support commercial process validation and characterization. You'll design experiments, analyze data, and mentor junior staff, ensuring excellence ... working with external contract organizations. + Proficiency in statistical methods for design of experiments (DOE) and data analysis, as well as statistical process… more
