- Bristol-Myers Squibb Company (Princeton, NJ)
- …ADME, DDI and drug development of all modalities including small molecules, protein therapeutics and novel modalities. The successful candidate will be the subject ... be hands-on experience in application of the high-resolution mass spectrometry (HRMS) and NMR in "cold" in vivo metabolism studies including FIH, and strategies in… more
- Dana-Farber Cancer Institute (Boston, MA)
- …transduction pathways. + Utilize structural methods such as X-ray crystallography, cryo-EM, or NMR for protein structure elucidation. + Perform protein ... The Eck Lab is dedicated to advancing our understanding of protein kinase regulation and cellular signal transduction through structural, biochemical, and… more
- The US Pharmacopeial Convention (USP) (Rockville, MD)
- …disabilities **Brief Job Overview** This is a hands-on, analyst position in USP's NMR Laboratory. The scientist will be an integral member of the nuclear Magnetic ... Resonance Spectroscopy ( NMR ) team and will assist in the execution of...with the following competencies and experience: + Ph.D. in Biomolecular/ Protein /Peptide related fields or Natural products isolation and structural… more
- University of Colorado (Aurora, CO)
- …Degree with a particular emphasis in either or both cryo-EM or NMR , molecular biology, and recombinant protein production. **Preferred Qualifications:** + ... in microbial metabolism. This position will involve advanced structural methods-particularly NMR spectroscopy and Cryo-EM-to explore protein structure, dynamics,… more
- University of Colorado (Aurora, CO)
- …**Examples of Duties Performed** + Molecular engineering (PCR) + Recombinant protein expression and purification (FPLC, HPLC) + Gel electrophoresis ( protein ... We utilize state-of-the-art techniques such as nuclear magnetic resonance ( NMR ) and cryo-electron microscopy (cryo-EM) to investigate atomic-resolution details of… more
- University of Washington (Seattle, WA)
- …RS may perform a variety of lab assays, including ELISAs, DNA extraction, PCR, protein counts, and Western Blots. The RS may provide support to Lab Technicians ... Scientist 1 will assist with metabolomics experiments involving the use of NMR and mass spectrometry, working under limited supervision to perform the following… more
- Dana-Farber Cancer Institute (Boston, MA)
- …chemistry with various 'Omics' techniques such as proteomics to study the pathways and protein complexes involved in the regulation of protein abundance via the ... While we consider various backgrounds, a strong interest in understanding differential protein expression in in vivo samples and development of methods to further… more
- Johns Hopkins University (Baltimore, MD)
- …a postdoctoral fellow interested in the discovery and mechanistic characterization of new G- protein coupled receptor (GPCR) ligands as drug leads with a variety of ... cutting-edge technologies. This work will involve membrane protein biochemistry, selection methodologies, structural biology (cryo-EM), and protein dynamics… more
- Lilly (Louisville, CO)
- …integrate cutting-edge tools, to extract insight from diverse experiments-SPR, NMR , crystallography, cryo-EM, virtual screens-and convert them into actionable ... **Additional Preferences:** + Hands-on experience with biophysical assays for protein characterization, binding analysis and Molecular Dynamics (MD). + Experience… more
- Boston College (Chestnut Hill, MA)
- …For this research we will use yeast genetics, live-cell imaging, protein dynamics, in vitro reconstitution, quantitative microscopy and mathematical modeling ... facilities include a nanofabrication, bioinformatics server, mass spectrometry, flowcytometry, NMR and X-ray crystallography facility. The following are examples of… more
- Old Dominion University (Norfolk, VA)
- …Knowledge of basic chemical principles such as organic structure, reactions, protein structure, biochemical processes, and basic physical chemical principles. + ... Demonstrated ability to carry out cryogen fills for mass spectrometry and NMR instruments + Significant direct experience handling chemicals and making chemical… more
- UTMB Health (Galveston, TX)
- … expression and purification, molecular biology, solution biophysics, NMR , X-ray crystallography, cryo-electron microscopy, bioinformatics, and computational ... chemistry (seehttp://www.utmb.edu/core). The University of Texas Medical Branch at Galveston (UTMB) is a major academic health sciences center located on the Texas Gulf Coast. Galveston has a mild, sub-tropical climate with outstanding recreational… more
