- University of Colorado (Aurora, CO)
- …of pluripotent stem cells into a variety of cell types, and CRISPR-Cas9-mediated gene targeting . Laboratory duties will involve receiving laboratory reagents and ... including melanoma and other skin cancers, and development of approaches to gene therapy in the skin. The Dermatopathology unit provides pathology services to… more
- Children's Mercy Kansas City (Kansas City, MO)
- …of the developing lung. Specific expertise in endothelial/vascular biology, Crispr/Cas9 gene targeting , use of single cell RNA-sequencing and bioinformatics ... and rodent work in the lung is preferred. Minimal requirements include a PhD degree with 3-5 years of post-graduate experience. The qualified applicant will work as part of a vibrant team consisting of physician-scientists, research technicians and PhD… more
- Bio-Techne (Minneapolis, MN)
- …will help develop and execute the commercial product strategy for Cell and Gene Therapy (CGT) products within Bio-Techne that offer significant promise to treat life ... of experience** + **Must have experience and understanding of the Cell and Gene Therapy market** + **Strong business acumen and aptitude for customer requirements**… more
- Lilly (Indianapolis, IN)
- …includes active investments in Oligonucleotide development, nanomedicines for tissue specific targeting and other gene delivery strategies. The drug product ... team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, Antibody Drug Conjugates and AAV and other non-viral vector delivery. We are seeking highly motivated professionals with an experience in developing… more
- Lilly (Indianapolis, IN)
- …includes active investments in Oligonucleotide development, nanomedicines for tissue specific targeting and other gene delivery strategies. The drug product ... team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, Antibody Drug Conjugates and AAV and other non-viral vector delivery. We are seeking highly motivated professionals with extensive experience in… more
- Rush University Medical Center (Chicago, IL)
- …will lead research efforts on human iPSC-based disease modeling or/and CRISPR gene perturbations. The job will perform experiments, analyze data, compile results, ... brain organoid cultures, high-content imaging, molecular biology, viral packaging, CRISPR gene perturbations and data analysis. Exemplifies the Rush mission, vision… more
- Editas Medicine (Cambridge, MA)
- …allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing. We believe our people are at the core of everything we do, ... must have a proven track record in the discovery and development of drugs targeting diseases of non-CNS/peripheral tissues at least through IND, with more than one… more
- Pfizer (New York, NY)
- **ROLE SUMMARY** The Director, Commercial Effectiveness for the Gene Therapy, Hemophilia and Rare Endocrine portfolio will be responsible for leading insights ... our Purpose Blueprint 2.0 **Lead Long-acting growth hormone (Ngenla), hemophilia, and gene therapy (GTx) sales, key account** **and commercial model planning:** +… more
- UCLA Fielding School of Public Health (Los Angeles, CA)
- …analyze data and lead projects in vascular biology, focusing on high-resolution gene expression profiling techniques. Responsibilities: + Collaborate with the PI and ... the lab. + Conduct innovative research in vascular biology, specifically targeting intracranial artery disease. + Utilize techniques like western blotting, qPCR,… more
- University of Rochester (Rochester, NY)
- …coordination and execution of experiments to establish the function and therapeutic targeting of various oncogenes of interest in myeloid leukemia to the principal ... immunohistochemistry. + Animal experiments, breeding and maintenance of wild-type and gene specific knockout mice under development. Xenografting cancer cells in… more
- Emory Healthcare/Emory University (Atlanta, GA)
- …for mRNA and other RNA-based drugs. The drugs may consist of vaccines, gene replacement therapies, mRNA-encoded antibodies, CRISPR gene editing therapies, and ... programs will be on extrahepatic delivery, and will therefore require both de- targeting the liver and increasing delivery to other tissues. Prepares and publishes… more
- University of Washington (Seattle, WA)
- …on the development, characterization, and refinement of vaccines and therapeutics targeting infectious diseases and cancers. This position will support projects ... Mouse handling, injections (IM, SQ, IP, RO), ear punching, vaccinations ( Gene Gun, IM, Intranasal, among other routes), challenge inoculations (influenza,… more
- University of Utah (Salt Lake City, UT)
- …keratan sulfates. * Chemical tools for studying and therapeutically targeting phosphorylation-dependent cellular signaling pathways. * Medicinal chemistry and ... biology targeted toward enzymes involved in immunology, neurological development, cancer, gene regulation, etc. * New tools for studying the biosynthesis,… more
- University of Colorado (Aurora, CO)
- …of our studies is to identify mechanisms of resistance to therapies targeting these pathways. The postdoctoral fellow will use unbiased approaches, including ... world, that have been molecularly characterized by genome-wide copy number and gene expression, histology, and mutations. Together, these tools and approaches will… more
- Burns & McDonnell (Columbus, OH)
- …and knowledge of life sciences markets and processes (fermentation, cell / gene therapy, API, blood products, purification, fill / finish, medical devices, etc) ... critical project objectives + Own the development of direct reports including targeting work for individual team members to expand their capabilities + Stay… more
- University of Pennsylvania (Philadelphia, PA)
- …to delivering therapeutics to the injured brain. Our lab packages drugs and gene therapy constructs (RNA) into nano-scale carriers (~100 nanometers in diameter), and ... in the department of pharmacology, with decades of experience on vascular targeting using engineered proteins and nanomedicine. Jake Brenner, MD, PhD is an… more
- University of Utah (Salt Lake City, UT)
- …ex vivo retina, calcium fluorescence imaging, virus-mediated cell targeting , immunohistochemistry, large-scale data analysis, and computational modeling. Successful ... preferred. Experience working with virus and virus mediated cell-, circuit- and gene manipulations is not required but would be considered advantageous. In… more
- University of Colorado (Aurora, CO)
- …generate different type of organoids + Design and execute CRISPR/Cas9-based gene editing experiments for validating disease-causing mutations. + Design and execute ... will participate in drug-screening studies to develop therapies for EDS by targeting pathways involved in collagen assembly and inflammation. The ideal applicant… more
- Johns Hopkins University (Baltimore, MD)
- …practical relationship to essential techniques in modern drug discovery, drug targeting and delivery, cellular and tissue analysis and characterization, and ... not be limited to, PCR optimization, quantitative real-time PCR, and control of gene expression by DNA sequencing in the clinical setup. The essential concepts… more
- Danaher Corporation (Washington, DC)
- …biological research to developing innovative vaccines, new medicines, and cell and gene therapies. At Cytiva you will be able to continuously improve yourself ... portfolio: developing new markets, succeeding in understanding assigned territory, targeting market segments, and introducing new products and workflow solutions… more