- University of Miami (Miami, FL)
- …electroporation and pronuclear or cytoplasmic injection of DNA and CRISPR gRNA/cas9; and gene targeting by electroporation and injection of ES/iPS cells into ... new services for the generation of transgenic, knock-out, knock-in and gene -edited mice, as well as developing and adapting state-of-the-art editing technologies… more
- University of Utah (Salt Lake City, UT)
- …The Mutation Generation and Detection ( MGD ) Core Facility and the Transgenic & Gene Targeting Mouse ( TGTM ) Core Facility work together to provide state ... of the art service and assistance in the field of mouse transgenics and gene targeting . The MGD core has the resources to carry out all the molecular techniques… more
- Johns Hopkins University (Baltimore, MD)
- …knowledge including nucleic acid/protein handling and hands-on experience in cell or animal gene targeting , genotyping. + Maintain the research animal colony and ... oversee compliance with ethical and regulatory guidelines for animal research. + Perform various organ/tissue collection followed by histological, immunohistochemical or in-situ hybridization experiments. + Perform computerized image analysis to collect and… more
- Lilly (Boston, MA)
- …includes active investments in Oligonucleotide development, nanomedicines for tissue specific targeting and other gene delivery strategies. The drug product ... team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, Antibody Drug Conjugates and AAV and other non-viral vector delivery. We are seeking highly motivated professionals with an experience in developing… more
- Lilly (Boston, MA)
- …includes active investments in oligonucleotide development, nanomedicines for tissue specific targeting and other gene delivery strategies. The drug product ... team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, antibody drug conjugates, AAV, and other non-viral vector delivery. We are seeking a highly motivated scientist with an interest in leading modeling… more
- Catalent Pharma Solutions (Harmans, MD)
- **Manager, Commercial Operations** Catalent Cell and Gene Therapy is looking to recruit **a Manager of Commercial Operations** to join our growing team in Maryland. ... and oncolytic viruses. Our FDA-licensed, state-of-the-art CGMP manufacturing facility for Gene Therapies is located on the Harmans/BWI campus. The campus, featuring… more
- University of Pennsylvania (Philadelphia, PA)
- …responsibilities may include research to complement and expand the world-leading retinal gene therapy program already well established at the Center for Hereditary ... regenerative medicine, genome engineering, neuroscience, or artificial intelligence directly targeting human conditions. This position is not intended for physicians… more
- University of North Carolina- Chapel Hill (Chapel Hill, NC)
- …to begin as early as May 1 2025. The Spanheimer lab studies how gene regulation impacts response to treatment in breast cancer. Particular areas of emphasis are ... from tumors and how we can prevent resistance by targeting unique vulnerabilities of those cells. The purpose of...testing in vitro models including CRISPR -CAS9 knockouts and gene regulation assays including mRNA sequencing and CUT and… more
- Mount Sinai Health System (New York, NY)
- …of first-in-class small molecule inhibitor/chemical probes as well as proteolysis targeting chimera (PROTAC) degraders for targeted protein degradation (TPD) and ... DNA, RNA, Protein isolation; conventional PCR and gel electrophoresis; RTqPCR; gene cloning experiments; virus preparation and cell transfection and infection;… more
- MD Anderson Cancer Center (Houston, TX)
- The research involves studies on; a) novel in vitro and in vivo targeting of DNA repair and genomic instability-induced replication stress mechanisms with the WEE1 ... translate this exciting avenue of research into possible clinical development of targeting the DNA repair and replication stress vulnerabilities in patients with… more
- J&J Family of Companies (San Diego, CA)
- …therapeutic modalities, such as small molecules, peptides, bi-specific antibodies, RNA- targeting therapeutics, cell-based therapy, and/or gene therapy, is ... preferred. + Experience representing toxicology/nonclinical safety on matrix project teams is preferred. + Board certification (eg Diplomate of the American Board of Toxicology (DABT)) is preferred. + Must have excellent oral and written communication skills.… more
- AbbVie (Cambridge, MA)
- …While existing technologies, such as bifunctional degraders, have transformed the targeting of intracellular proteins, the degradation of cell surface proteins ... research. + Experience with advanced molecular biology techniques including CRISPR/Cas9 gene editing, flow cytometry, and confocal microscopy. + Strong track record… more
- Dana-Farber Cancer Institute (Boston, MA)
- The Cancelas Lab seeks a Postdoctoral Scientist to study leukemogenesis and targeting in leukemia. The applicant should have a doctoral degree in Biology, Molecular ... all - of the following techniques: PCR, molecular cloning, viral transduction, gene editing, immunoblotting, cell culture, colony-formation assays, ex vivo and in… more
- BD (Becton, Dickinson and Company) (Milpitas, CA)
- …the BD Rhapsody Single Cell Analysis Platform & Assays (WTA, Targeted gene expression, TCR/BCR, ATAC-seq, BD AbSeq Portfolio, Multiplexing kits and other new ... record in strategic marketing, including market segmentation, customer segmentation, targeting , value proposition development, positioning, promotion, pricing, forecast, budget… more
- University of Rochester (Rochester, NY)
- …and are at the cutting edge of promising new gene therapies. The Division of Multiple Sclerosis and Neuroimmunology ... therapeutics of MS. The Division oversees research assessing novel immunotherapies targeting multiple steps in the pathogenesis of MS, evaluating new symptomatic… more
- University of Utah (Salt Lake City, UT)
- …in gene regulation, virus chromatin interactions and drug discovery targeting EBV and KSHV proteins. **Responsibilities** The successful applicant will be ... expected to contribute to planning experiments and writing manuscripts and grant applications in addition to carrying out bench research. The job will require preparation of manuscripts for publication, regular presentations at group meetings, assistance with… more
- University of Pennsylvania (Philadelphia, PA)
- …outlined on our website (www.brennerbioengineeringlab.com), our lab packages drugs and gene therapy vectors into nano-scale carriers (~100 nanometers in diameter), ... inpatient and outpatient stroke neurology service, and 80% developing novel brain targeting strategies to treat acute brain illness. Contact: Jake Brenner, MD, PhD… more
- University of Pennsylvania (Philadelphia, PA)
- …to delivering therapeutics to the injured brain. Our lab packages drugs and gene therapy constructs (RNA) into nano-scale carriers (~100 nanometers in diameter), and ... in the department of pharmacology, with decades of experience on vascular targeting using engineered proteins and nanomedicine. Jake Brenner, MD, PhD is an… more
- Johns Hopkins University (Baltimore, MD)
- …practical relationship to essential techniques in modern drug discovery, drug targeting and delivery, cellular and tissue analysis and characterization, and ... not be limited to, PCR optimization, quantitative real-time PCR, and control of gene expression by DNA sequencing in the clinical setup. The essential concepts… more
- Penn State Health (Hershey, PA)
- …the development and clinical translation of novel vaccine and cellular immunotherapies targeting pediatric solid tumors. The director will also spearhead gene ... therapy initiatives for non-malignant hematologic conditions, particularly sickle cell disease, ensuring integration of translational research with compassionate, high-quality clinical care. The successful candidate will foster collaborations across basic… more