- Kelly Services (Boston, MA)
- …responsible for executing the clinical development strategy for our client's innovative gene therapies targeting cardiovascular diseases. This individual will be ... strategic planning, design, and execution of clinical trials in the cardiac gene therapy programs. * Provide expert clinical operations leadership, ensuring that… more
- Kelly Services (Boston, MA)
- …responsible for executing the clinical development strategy for our client's innovative gene therapies targeting cardiovascular diseases. This individual will be ... strategic planning, design, and execution of clinical trials in the cardiac gene therapy programs. + Provide expert clinical operations leadership, ensuring that… more
- University of Miami (Miami, FL)
- …electroporation and pronuclear or cytoplasmic injection of DNA and CRISPR gRNA/cas9; and gene targeting by electroporation and injection of ES/iPS cells into ... new services for the generation of transgenic, knock-out, knock-in and gene -edited mice, as well as developing and adapting state-of-the-art editing technologies… more
- University of Utah (Salt Lake City, UT)
- …The Mutation Generation and Detection ( MGD ) Core Facility and the Transgenic & Gene Targeting Mouse ( TGTM ) Core Facility work together to provide state ... of the art service and assistance in the field of mouse transgenics and gene targeting . The MGD core has the resources to carry out all the molecular techniques… more
- Cedars-Sinai (Beverly Hills, CA)
- …such as electroporation of embryos with CRISPR mixture. + Ability to design gene targeting strategies using conventional ES or more advanced CRISPR technologies. ... + Ability to schedule day-to-day operations. + Cryopreservation and cryorecovery of mouse sperm and embryos. + Ability to come in on weekends (1-2 times a month) and early mornings (4-8 times a month) for animal care and procedures as needed.… more
- Stanford University (Stanford, CA)
- …spearhead cutting-edge research initiatives to design, implement, and optimize CRISPR-based gene -editing therapies targeting RBM20. You will leverage the ... about pioneering therapeutic strategies at the forefront of cardiac gene editing and eager to shape the future of...or a related field. + Demonstrated expertise in CRISPR-based gene -editing technologies and a solid background in cardiac biology.… more
- University of Miami (Miami, FL)
- …genetic engineering services. These services include the use of CRISPR/Cas9 targeting to produce gene knockouts, conditional knockouts, single-point mutations, ... and insertions and gene fusions, also simultaneously mutating multiple genes in a...mice, knock-in (KI) mice generation using traditional ES cell targeting including C57BL6 ESCs; ES cell, tetraploid and iPS… more
- Lilly (Indianapolis, IN)
- …includes active investments in Oligonucleotide development, nanomedicines for tissue specific targeting and other gene delivery strategies. The drug product ... team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, Antibody Drug Conjugates and AAV and other non-viral vector delivery. We are seeking a highly motivated Scientist with an interest or experience in… more
- Lilly (Boston, MA)
- …includes active investments in Oligonucleotide development, nanomedicines for tissue specific targeting and other gene delivery strategies. The drug product ... team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, Antibody Drug Conjugates and AAV and other non-viral vector delivery. We are seeking highly motivated professionals with an experience in developing… more
- University of Utah (Salt Lake City, UT)
- …cytometry (eg, FACS , CyTOF). 3. Proficiency in viral and non-viral gene delivery systems (eg, lentiviral transduction, CRISPR -based modifications). 4. Experience ... in CAR T cell therapy, gene editing, or immunotherapy research is highly desirable. 5....cell engineering, including improving CAR T cell persistence, antigen targeting , and allogeneic compatibility. 7. Troubleshoot variability in cell… more
- Sumitomo Pharma (Columbus, OH)
- …oncology, urology, women's health, rare diseases, psychiatry & neurology, and cell & gene therapies. With several marketed products in the US, Canada, and Europe, ... scientific content. The position will focus on pre-planning, strategic targeting , diversified engagement, efficient tool utilization, maximizing on-site time, and… more
- University of Pennsylvania (Philadelphia, PA)
- …responsibilities may include research to complement and expand the world-leading retinal gene therapy program already well established at the Center for Hereditary ... regenerative medicine, genome engineering, neuroscience, or artificial intelligence directly targeting human conditions. This position is not intended for physicians… more
- University of North Carolina- Chapel Hill (Chapel Hill, NC)
- …to begin as early as May 1 2025. The Spanheimer lab studies how gene regulation impacts response to treatment in breast cancer. Particular areas of emphasis are ... from tumors and how we can prevent resistance by targeting unique vulnerabilities of those cells. The purpose of...testing in vitro models including CRISPR -CAS9 knockouts and gene regulation assays including mRNA sequencing and CUT and… more
- Cleveland Clinic (Cleveland, OH)
- …on the roles of the actin cytoskeleton, myosin motors, and upstream cytoskeleton- targeting signaling cascades in disassembly and reformation of tight and adherens ... Epithelila cell culture, Immunofluorescence labeling and confocal microscopy, Molecular biology, Gene knockdown or knockout, Viral vectors for gene transduction,… more
- Mount Sinai Health System (New York, NY)
- …of first-in-class small molecule inhibitor/chemical probes as well as proteolysis targeting chimera (PROTAC) degraders for targeted protein degradation (TPD) and ... DNA, RNA, Protein isolation; conventional PCR and gel electrophoresis; RTqPCR; gene cloning experiments; virus preparation and cell transfection and infection;… more
- Bill and Melinda Gates Foundation (Seattle, WA)
- …and invest in the innovation to improve the performance, coverage, and targeting of interventions for all three, including 'moonshots' like genetically modified ... vaccines. A fundamental enabler of interventions is accurate, timely, and geo-localized targeting . To improve this, we advocate for and support countries in their… more
- J&J Family of Companies (Spring House, PA)
- …therapeutic modalities, such as small molecules, peptides, bi-specific antibodies, RNA- targeting therapeutics, cell-based therapy, and/or gene therapy, is ... preferred. + Experience representing toxicology/nonclinical safety on matrix project teams is preferred. + Board certification (eg Diplomate of the American Board of Toxicology (DABT)) is preferred. + Must have excellent oral and written communication skills.… more
- Bristol Myers Squibb (Seattle, WA)
- …T cell engineering is strongly desired + Working knowledge of multi antigen targeting using T cell-based approaches (eg dual/tri-specific CAR T) is preferred. + ... cell signaling, high throughput screening, automation (liquid handling robots), CRISPR gene editing, and/or imaging technologies is desired + Skilled in generating,… more
- Lilly (Indianapolis, IN)
- …**Key Responsibilities:** + Design and perform in vitro experiments on RNA- targeting therapeutics, role entails work across multiple cell lines and primary ... Skills in molecular biology techniques, including mammalian cell culture, qPCR, and gene and protein analysis + Proficiency in data analysis software and statistical… more
- University of Pennsylvania (Philadelphia, PA)
- …to delivering therapeutics to the injured brain. Our lab packages drugs and gene therapy constructs (RNA) into nano-scale carriers (~100 nanometers in diameter), and ... in the department of pharmacology, with decades of experience on vascular targeting using engineered proteins and nanomedicine. Jake Brenner, MD, PhD is an… more