- Merck & Co. (South San Francisco, CA)
- …optimization in support of our biotherapeutic portfolio drug discovery programs. The Principal Scientist , Computational Protein Engineering role will be a key ... to guide antibody and protein design and optimizationApply cutting-edge AI /machine learning models to support drug discovery and engineering projectsIntegrate… more
- Microsoft Corporation (Mountain View, CA)
- …Security products, turning cutting-edge research into dependable, production-ready capabilities. As a ** Principal Applied Scientist - Security AI Models** , ... deepen model reasoning and tool-use skills, and embed responsible AI and compliance into every stage of the workflow....and help shape the next generation of secure, trustworthy AI for our customers. Microsoft's mission is to empower… more
- Microsoft Corporation (Mountain View, CA)
- …Security products, turning cutting-edge research into dependable, production-ready capabilities. As a ** Principal Applied Scientist - Security AI Models** , ... deepen model reasoning and tool-use skills, and embed responsible AI and compliance into every stage of the workflow....and help shape the next generation of secure, trustworthy AI for our customers. _Microsoft's mission is to empower… more
- Microsoft Corporation (Mountain View, CA)
- …and intelligence services to transform how Microsoft collects, generates, manages, and shares AI training data. We are seeking Principal Applied Scientists to ... Join Microsoft's CoreAI team to build the AI Data Platform, the foundation for secure, scalable,...secure, scalable, reusable datasets that power model development. The AI Data Platform team's mission is to build a… more
- Genentech (South San Francisco, CA)
- …in target identification, disease understanding, and therapeutic exploration. As a Senior/ Principal Scientist , you will lead scientific initiatives that bridge ... expert and innovator, capable of shaping scientific direction and organizational strategy. Principal Scientist + PhD (or equivalent) in a quantitative discipline… more
- Amazon (San Francisco, CA)
- …AI pioneers to lead key initiatives in robotic intelligence. As a Principal Applied Scientist , you'll spearhead the development of breakthrough foundation ... Join the next revolution in robotics at Amazon's Frontier AI & Robotics team, where you'll work alongside world-renowned...global scale, please apply! About the team At Frontier AI & Robotics, we're not just advancing robotics -… more
- Amazon (Palo Alto, CA)
- …possible with AI , join us in shaping the future of advertising. The principal scientist in this position will focus on designing, developing and launching ... the boundary of what's possible in these fields. Key job responsibilities As a Principal Applied Scientist for the team, you will drive appropriate technology… more
- Amazon (Palo Alto, CA)
- Description The Sponsored Products (SP) team is looking for a Principal Scientist to help our millions of shoppers intuitively navigate our vast inventory by ... in product and technical innovations every day! As a Principal Scientist in Sponsored Products, you will...abreast of the latest developments in the space of AI /ML/GenAI modeling and identify opportunities to improve the efficiency… more
- Amgen (South San Francisco, CA)
- …Join us and transform the lives of patients while transforming your career. ** Principal Scientist - Clinical Pharmacology, Modeling & Simulation** **What you ... Modeling & Simulation Department at Amgen is seeking a Principal Scientist . In this vital role, you...modeling - integrated with emerging Machine Learning and Generative AI approaches - to innovatively guide optimal clinical drug… more
- Amazon (San Francisco, CA)
- …General Intelligence (AGI) team is looking for a passionate, talented, and inventive Principal Applied Scientist with a strong deep learning background, to lead ... the development of industry-leading technology with multimodal systems. As a Principal Applied Scientist , you are a trusted part of the technical leadership. You… more
- Microsoft Corporation (Mountain View, CA)
- …and other Microsoft Copilots. We are seeking an entrepreneurial and creative Principal Applied Scientist to lead groundbreaking research projects, taking these ... The Data and AI team in Microsoft's Developer Division is working on the future of AI for Developers! We are a diverse, entrepreneurial and multi-disciplinary… more
- Microsoft Corporation (Mountain View, CA)
- …focused on strengthening service availability and reliability. We are hiring an experienced Principal Data Scientist Manager to join our agile and diverse team. ... service quality and generate insights to help mitigate customer-impacting issues. As a Principal Data Scientist Manager, you will lead efforts to develop… more
- Microsoft Corporation (Mountain View, CA)
- The Bing organization is looking for a ** Principal Data Scientist ** . The team is pushing the boundaries regarding our understanding for how users engage with ... and even multiplicative impact on the org. As a Principal Data Scientist in this team, you...at work and beyond. Starting January 26, 2026, Microsoft AI (MAI) employees who live within a 50- mile… more
- Microsoft Corporation (San Francisco, CA)
- The Outlook Data and AI Platform team is seeking a Principal Data Science Leader to shape our data strategy, drive innovation, and build the data culture that ... powers Copilot and AI transformation at scale. This leader will be responsible...impact across engineering, product, and customer experiences. As a ** Principal Data Scientist ** , you will partner… more
- Gilead Sciences, Inc. (Foster City, CA)
- …together. **Position Overview:** We are seeking a highly motivated and creative Principal Scientist to support Gilead's growing Oncology targeted large molecule ... + Proficiency in data analysis tools and statistical software; experience with AI /ML applications is a plus + Strong project management skills with ability… more
- Gilead Sciences, Inc. (Foster City, CA)
- …Description** **Position Overview:** We are seeking a highly motivated and creative Principal Scientist to lead our Lipid Nanoparticle (LNP) technology ... + Proficiency in data analysis tools and statistical software;experience with AI /ML applications in drug formulation optimization isa plus. + Exceptional… more
- Microsoft Corporation (Mountain View, CA)
- …science problems across users, advertisers, and publishers. We are looking for a ** Principal Data Scientist ** leader, creative modeling geeks who are willing to ... where everyone can thrive at work and beyond. Starting January 26, 2026, Microsoft AI (MAI) employees who live within a 50- mile commute of a designated Microsoft… more
- Genentech (South San Francisco, CA)
- …for the Translational Safety Digital Pathology group. The successful Sr Principal Sci-Pathologist candidate will lead efforts focused on driving applications for ... stage through marketed products. This includes managing a team of AI /ML scientists to create and implement novel, state-of-the-art analytical and computational… more
- Microsoft Corporation (Mountain View, CA)
- …open-source software assets that contribute to the Microsoft platform. As a ** Principal ** **Data Scien** **tist** , you will help drive high-impact engineering ... projects with our customers and their partners, transforming their missions using AI and other cloud-based solutions and services. Data scientists have data… more
- MongoDB (Palo Alto, CA)
- …applications by helping them modernize legacy workloads, embrace innovation, and unleash AI . Our industry-leading developer data platform, MongoDB Atlas, is the only ... organizations, like Samsung and Toyota, trust MongoDB to build next-generation, AI -powered applications. **Job Description:** The mission of MongoDB Research is to… more
