• Merck & Co. (South San Francisco, CA)
    Job DescriptionWe are seeking an exceptional computational protein engineer to join the Discovery Biologics Protein Engineering department in South San Francisco to ... in support of our biotherapeutic portfolio drug discovery programs. The Principal Scientist, Computational Protein Engineering role will be a key contributor… more
    HireLifeScience (08/22/25)
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  • Principal Performance

    Zoom (San Jose, CA)
    …for this position What you can expectZoom is seeking a highly experienced and impactful Principal Performance Engineer to join our DevOps/SRE team. In this ... you will be responsible for driving the optimization of backend service performance across Zoom's expansive platform. You will work closely with development teams,… more
    Zoom (10/16/25)
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  • Software Engineer

    Broadcom (Palo Alto, CA)
    Performance Team at VMware Cloud Foundation (VCF) in Broadcom we are looking for a Principal Performance Engineer (ICB5) to join our team! You will have ... agility of a public cloud with the security and performance of a private cloud. Modern infrastructures, accelerated application...different stacks in VCF. You will drive scalability and performance of VCF which includes flagship products such as… more
    Broadcom (09/27/25)
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  • Senior Principal Mechanical Engineer

    Roche (South San Francisco, CA)
    …and driving change when performance does not meet expectations. + The Senior Principal Mechanical Engineer will also be the SSF site expert on industry ... **The Position** As a Senior Principal Mechanical Engineer at Genentech, you'll...adopting technologies and delivery approaches which improve building systems performance , cost effectiveness, and reliability. + This role will… more
    Roche (10/14/25)
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  • Principal /Senior Principal Software…

    Genentech (South San Francisco, CA)
    …field, or equivalent experience and 7+ years of experience in software engineering ( Principal Software Engineer ); 12+ years of experience (Sr. Principal ... the primary location of California is $162,600 - $302,000 ( Principal Software Engineer ) and $189,200 - $351,400...bonus may be available based on individual and Company performance . This position also qualifies for the benefits detailed… more
    Genentech (09/06/25)
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  • Principal Information Systems…

    City and County of San Francisco (San Francisco, CA)
    …the minimum qualifications. Application Deadline: Continuous How to Apply: Applications for Principal Information Systems Engineer - Systems Specialty are only ... as an enterprise networking backbone or platform. The 1044 Principal Systems Engineer is the highest level...complex systems or networks. Essential Duties: 1. Oversees the performance of day-to-day operational support for server, storage or… more
    City and County of San Francisco (08/08/25)
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  • Principal Information Systems…

    City and County of San Francisco (San Francisco, CA)
    …minimum qualifications. Application Deadline: Continuous How to Apply: Applications for Principal Information Systems Engineer - Applications Specialty are only ... that integrate these systems together as an enterprise networking backbone. The 1044 Principal Applications Engineer is the highest level in the Engineer more
    City and County of San Francisco (08/08/25)
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  • Principal Information Systems…

    City and County of San Francisco (San Francisco, CA)
    …the minimum qualifications. Application Deadline: Continuous How to Apply: Applications for Principal Information Systems Engineer - Networks Specialty are only ... that integrate these systems together as an enterprise networking backbone. The 1044 Principal Networks Engineer is the highest level in the Engineer more
    City and County of San Francisco (08/08/25)
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  • Principal Information Systems…

    City and County of San Francisco (San Francisco, CA)
    …the minimum qualifications. Application Deadline: Continuous How to Apply: Applications for Principal Information Systems Engineer - Security Specialty are only ... that integrate these systems together as an enterprise networking backbone. The 1044 Principal Security Engineer is the highest level in the Engineer more
    City and County of San Francisco (08/08/25)
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  • Senior/ Principal Software Engineer

    Genentech (South San Francisco, CA)
    …4+ years of professional experience in backend or data engineering roles(Senior Software Engineer ) ; 7+ ( Principal Software Engineer ). + Excellent ... position based on the primary location of California $142,500-264,700 (Senior Software Engineer ) and $162,600-302,000 ( Principal Software Engineer ). Actual… more
    Genentech (09/06/25)
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  • Principal Staff Software Engineer

    LinkedIn (Mountain View, CA)
    …that power the visibility, cost attribution and planning of LinkedIn Infrastructure. As a Principal Engineer , they will mentor team members, uphold a high bar ... Responsibilities + We take an engineering-first approach to elevate infrastructure. As a Principal Engineer , you'll be driving the strategy to reduce the total… more
    LinkedIn (09/30/25)
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  • Senior/ Principal Software Engineer

    Genentech (South San Francisco, CA)
    …and 4+ years of professional experience in full-stack software development (Senior Software Engineer ); 7+ years ( Principal Software Engineer ). + Strong ... position based on the primary location of California $142,500-264,700 (Senior Software Engineer ) and $162,600-302,000 ( Principal Software Engineer ). Actual… more
    Genentech (09/06/25)
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  • Principal Software Engineer

    Microsoft Corporation (Mountain View, CA)
    …major Microsoft products, including Office, Windows, Bing, SQL Server, and Dynamics. As a Principal Engineer on the team, you will have the opportunity to work ... on a collaborative and inclusive culture. We own inference performance of OpenAI and other state of the art...locations considered for very strong candidates. **Responsibilities** As a Principal Engineer on the team the common… more
    Microsoft Corporation (10/14/25)
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  • Principal Software Engineer

    Microsoft Corporation (Mountain View, CA)
    …365, Bing, SQL Server, VSCode, Cognitive Service, Copilot+ PC, and many others. As the Principal Software Engineer on our team, you would have the opportunity to ... Microsoft develops software that pushes the cutting edge of performance and experience in machine learning in production and...can thrive at work and beyond. **Responsibilities** As a Principal Software Engineer on the team the… more
    Microsoft Corporation (10/09/25)
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  • Principal , UX Designer / Engineer

    Walmart (San Bruno, CA)
    **Position Summary ** **What you'll do ** ** Principal UX Designer / Engineer , AI Systems - Design Organization** **What you'll do** As a Principal UX ... Develop reliable backend services in Python and Node.js, focusing on performance , resilience, and observability. Harden prototypes into production-ready, secure, and… more
    Walmart (09/23/25)
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  • Principal Engineer , VCF Cluster…

    Broadcom (Palo Alto, CA)
    …and technical excellence. **Job Summary** We are seeking a highly experienced and visionary Principal Engineer to join our VCF Cluster Management team. In this ... solutions. We are dedicated to building robust, scalable, and high- performance distributed systems that empower enterprises to achieve their...at least 5 years in a lead architect or principal engineer role focusing on distributed systems.… more
    Broadcom (07/29/25)
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  • Principal Software Engineer

    Microsoft Corporation (Mountain View, CA)
    …that will manage and optimize the Cloud infrastructure. We are looking for a ** Principal Software Development Engineer ** to join the team. **Why Join AHSI at ... team is looking for a highly motivated and experienced Principal Software Development Engineer to join our...Engineer to join our mission of building robust, high- performance system software. This role is for engineers with… more
    Microsoft Corporation (10/11/25)
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  • Engineer Principal - Citywide

    City and County of San Francisco (San Francisco, CA)
    …contact Tamara Ranney at ###@sfgov.org. Under general administrative direction, the Principal Engineer /Architect manages, plans, assigns and directs the ... inspection and construction personnel. + Supervising subordinate personnel, completing performance appraisals, and participating in the disciplinary process when… more
    City and County of San Francisco (10/01/25)
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  • Principal Software Engineer

    Unity Technologies (San Francisco, CA)
    **San Francisco, CA, USA** ** Principal Software Engineer - Reporting and Business Intelligence** Location San Francisco, CA, USA Department Data & Analytics ... than 3.7 billion times per month. We're seeking a Principal Data Engineer to lead the design...BigQuery, Apache Flink, Apache Druid, and Flair to build high- performance , real-time, and self-service analytics solutions. **What You'll Be… more
    Unity Technologies (08/27/25)
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  • R & D Software Engineer - Principal

    Broadcom (Palo Alto, CA)
    …Role: A Visionary Technical Leader** We are seeking a highly experienced and visionary Principal Engineer to join our VCF vCenter team. In this pivotal role, ... solutions. We are dedicated to building robust, scalable, and high- performance distributed systems that empower enterprises to achieve their...at least 5 years in a lead architect or principal engineer role focusing on distributed systems… more
    Broadcom (09/18/25)
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